MOUSE MONOCLONAL ANTIBODY TO: HUMAN CYTOKERATIN 1-3

PRODUCT CODE RDI-CBL222 $375.00/vial 200ug

CLONE AE8

ISOTYPE IgG1

SOURCE Mouse ascitic fluid

PURIFICATION METHOD Ion exchange chromatography followed by ammonium sulphate precipitation

SPECIFICITY This antibody recognizes human cytokeratin 1-3. Cytokeratin 1-3 is expressed by several stratified squamous epithelia such as vagina, tongue, oral mucosa, oesophagus, epidermis and urothelium of bladder and squamous cell carcinomas such as cervical carcinomas and transitional cell carcinoma of bladder

APPLICATIONS

*Identification of cytokeratin 1-3 expressing tissues by indirect immunofluorescence staining or by indirect immunoperoxidase staining of frozen sections

*CBL222 is excellent for identifying various forms of squamous metaplasia and cell type heterogenety

REFERENCES

Sun, T-T. et al. Cancer Cell 1, 169-76 (1984)

Cooper, D. et al. Lab. Invest. 52, 243-56 (1985)

PRESENTATION The monoclonal is presented at a concentration of 200µg @ 1mg/ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.

STORAGE For use within 1 month of purchase store at +4oC, for long term storage aliquot antibody into small volumes and store at -20oC.