rev:January 2, 1997

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ANTIBODIES  

(anti-Human and others as indicated)

RDI Divison of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


Mouse ANTI-LEWISa ANTIGEN MONOCLONAL


PRODUCT CODE :RDI-CBL205    $375.00/vial 200ug


CLONE: PR5C5


ISOTYPE: IgG1


SOURCE: Mouse ascitic fluid.


PURIFICATION METHOD: Ion exchange chromatography following ammonium sulphate precipitation.


SPECIFICITY: Human colonic mucus, epithelial cells and cell membranes. Reactive with Lewisa antigen as judged by oligo-saccharide inhibition tests.


APPLICATIONS:

* Histological diagnosis of colon disorders. Wide reactivity with bowel, small intestine, stomach and also colo-rectal tumours.

* Reactive with formalin-fixed paraffin wax embedded sections.

* Histology, potentially serum diagnosis.


REFERENCES: Richman, P.R. and Bodmer, W.F. (1987). Int. J. Cancer 39, 317-328


PRESENTATION: Each monoclonal is delivered in a sealed vial at a concentration of 200µg/2ml in phosphate buffered saline solution containing 10mM sodium azide and 1mg/ml BSA. We recommend that each laboratory determine an optimum working titre for use in its particular application.


STORAGE: Purified monoclonal antibodies are generally stable for long periods at 4oC. However repeated warming to room temperature and re-cooling may result in a loss of activity and hence effective working titre. It is recommended that monoclonal antibodies are aliquotted upon receipt and then stored at -20C. After thawing they should then be used as a stock solution for up to 60 days. Dilute working solutions are best prepared on the day of use.


For research use only. Not supplied for use in human diagnostic or therapeutic procedures


Other Antibodies of Interest:

RE: Mucin & related Antibodies


#RDI-CBL204             mouse anti-human milk mucin core antigen SM3

$375.00/200ug             (see ref: Canc. Res. 47, 5476-82 (1987) ).


#RDI-CBL205             mouse anti-Lewis A antigen clone PR5C5

$375.00/200ug             (reacts with lewis A antigen, colonic mucus, epithelial cells and cell membranes).


#RDI-PanMuc-B12      mouse anti-human pan-mucin producing cell

$500.00/100Tests         clone b-12 useful for identifying mucin-like carcinoma antigens (MCA) produced by various tumors and certain healthy glandular cells. In combination with other BMA markers for inflammation staging or investigating neo- vascularization processes, clone b-12 is a valuable tool for studying tumor growth/regression. mIgG1k, suitable for frozen and paraffin sections.


RDI-MUC1abm           mouse anti-human mucin-1 glycoprotein MUC-1 Ma695

$375.00/1ml                 (see ref: Human Pathology 25, 364-372 (1994).


RDI-MUC1CORabm    mouse anti-human mucin-1 core glycoprotein Ma552

$375.00/1ml                  (see ref: Human Pathology 25, 364-372 (1994).


RDI-MUC2abm             mouse anti-mucin-2 glycoprotein MUC-2 clone Ccp58

$375.00/1ml                   (useful in colonic and gastric tumours to detect MUC-2 also known as intestinal-Mucin Related

                                       Protein)

RDI-MUCGASabm        mouse anti-human gastric mucin clone 45M1

$438.00/                         1ml reacts with surface epithelium of the normal   gastrointestinal tract, but not with normal

                                       colon. The antibody also reacts with fetal colonic mucosa, adenomas, hyperplastic polyps,                                                    carcinomas and mucosa adjacent to carcinomas.


RDI-PSAabmX               mouse anti-human PSA (Prostate Specific Antigen)

$375.00/vial                     (suitable for parrafin embedded tissues) 1ml lyophilized


See also antibodies again human milk fat globule HMFG1 and HMFG2



RDI Divison of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (800) 370-2222 or (201) 584-7093

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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