rev:January 2, 1997
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ANTIBODIES
(anti-Human and others as indicated)
Research Diagnostics Inc offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
Mouse ANTI-MILK MUCIN CORE ANTIGEN
PRODUCT CODE :RDI-CBL204 $300.00/vial
CLONE: SM-3
ISOTYPE: IgG1
SOURCE: Mouse ascitic fluid.
PURIFICATION METHOD: Ion exchange chromatography following ammonium sulphate precipitation.
SPECIFICITY: Human milk mucin core protein.
APPLICATIONS:
* Diagnosis, serum monitoring and therapy of breast cancer. Very little reactivity with normal tissue. Potentially useful as a targetting antibody. Reacts also with colon and ovarian cancer.
* Immunohistology (reactive with methacarn-fixed tissue).
* Serum assays
* Immunotargetting of radiolabels, drugs or toxins to tumours
REFERENCES: Burchell, J. et al. Canc. Res. 47, 5476 - 82 (1987)
PRESENTATION: Each monoclonal is delivered in a sealed vial at a concentration of 200µg/2ml in phosphate buffered saline solution containing 10mM sodium azide and 1mg/ml BSA. We recommend that each laboratory determine an optimum working titre for use in its particular application.
STORAGE: Purified monoclonal antibodies are generally stable for long periods at 4oC. However repeated warming to room temperature and re-cooling may result in a loss of activity and hence effective working titre. It is recommended that monoclonal antibodies are aliquotted upon receipt and then stored at -20C. After thawing they should then be used as a stock solution for up to 60 days. Dilute working solutions are best prepared on the day of use.
For research use only. Not supplied for use in human diagnostic or therapeutic procedures
RE: Mucin & related Antibodies
#RDI-CBL204 mouse anti-human milk mucin core antigen SM3
$300.00/200ug (see ref: Canc. Res. 47, 5476-82 (1987) ).
#RDI-CBL205 mouse anti-Lewis A antigen clone PR5C5
$300.00/200ug (reacts with lewis A antigen, colonic mucus, epithelial cells and cell membranes).
#RDI-PanMuc-B12 mouse anti-human pan-mucin producing cell
$400.00/100Tests clone b-12 useful for identifying mucin-like carcinoma antigens (MCA) produced by various tumors and certain healthy glandular cells. In combination with other BMA markers for inflammation staging or investigating neo- vascularization processes, clone b-12 is a valuable tool for studying tumor growth/regression. mIgG1k, suitable for frozen and paraffin sections.
RDI-MUC1abm mouse anti-human mucin-1 glycoprotein MUC-1 Ma695
$300.00/1ml (see ref: Human Pathology 25, 364-372 (1994).
RDI-MUC1CORabm mouse anti-human mucin-1 core glycoprotein Ma552
$300.00/1ml (see ref: Human Pathology 25, 364-372 (1994).
RDI-MUC2abm mouse anti-mucin-2 glycoprotein MUC-2 clone Ccp58
$300.00/1ml (useful in colonic and gastric tumours to detect MUC-2 also known as intestinal-Mucin Related
Protein)
RDI-MUCGASabm mouse anti-human gastric mucin clone 45M1
$350.00/ 1ml reacts with surface epithelium of the normal gastrointestinal tract, but not with normal
colon. The antibody also reacts with fetal colonic mucosa, adenomas, hyperplastic polyps, carcinomas and mucosa adjacent to carcinomas.
RDI-PSAabmX mouse anti-human PSA (Prostate Specific Antigen)
$300.00/vial (suitable for parrafin embedded tissues) 1ml lyophilized
See also antibodies again human milk fat globule HMFG1 and HMFG2
Research Diagnostics Inc
Pleasant Hill Road
Flanders NJ 07836
phone (800) 631-9384 or (201) 584-7093
fax (201) 584-0210
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