rev: October 1, 2001
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ANTIBODIES
(anti-Human and others as indicated)
RDI Divison of researchd Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
IL-8 Receptor (IL-8R)- ANTISERA see polyclonals and monoclonals below
DATA SHEET: mouse anti-human IL8RB (Interleukin 8 Receptor Beta Chain) CXCR2
Catalog#: RDI-IL8RB-483 $535.00/vial
Package Size: 500ug purified with 5% trehalose. Reconstitute with sterile PBS.
Species: mouse IgG2A CLONE: Activity: Reacts with human interleukin 8 receptor Beta (IL- 8RB) Does not cross react with CXCR1 (IL-8RA)
Application: Flow cytometry, Immunohistochemistry, and Neutralization
Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.
Catalog#: RDI-IL8RA-5A12 $531.00/vial - DISCONTINUED
FITC labeled (with azide) cat#RDI-IL8RA-5AFt $625.00/0.2mg (Biotin & PE on request)
* no azide formulation cat#RDI-IL8RA-5A12X
$781.00/vial - DISCONTINUED
Package Size: 500ug purified with 0.1% sodium azide*. (sodium azide is toxic,
dilute azide compounds with copious amounts of water when disposing in drain
to avoid accumulation of explosive deposits-avoid contact with acids.)
Prep: purified from tissue culture supernatant via Protein G affinity
chromatography.
Species: mouse IgG2b
CLONE: 5A12
Activity: Reacts with human interleukin 8 receptor alpha (IL- 8RA), a G protein
linked seven transmembrane domain protein, expressed on monocytes and
granulocytes. It is also expressed on a subset of T cells. IL-8RA and IL-8RB
are high affinity receptors for IL-8.
Application: -Indirect immunofluorescence cell surface staining
-blocking: NOTE: Use azide free formulation for blocking. It has been found that the anti-IL8Ra antibody cat#RDI-IL8RA-5A12 blocks IL8 mediated chemotaxis more effectively than anti-IL-8RB. A combination of both is recommended for blocking chemotactic activity. A concentration of 0.8- 15ug/ml each of anti-IL8RA and anti-IL8RB can block by 50% the chemotaxis of human neutrophil induced by 50ng/ml rhIL-8.
Titer for each application
References: 1) Eur J. immunol. 26:640
Storage: Store at 4 DEG C.
Precautions: For In vitro research Use Only. Not for use in or on humansor
animals or for diagnostics. It is the responsibility of the user to comply
with all local/state and Federal rules in the use of this product. We are
not responsible for any patent infringements that might result with the use
of or derivation of this product.
San Jose, 95123 CA Snell ave 658
USA
or 408-780-0908
EMAIL:margaret@cellular-research.com
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