NOTE: 10% Discount on purchases of 3 or more any combination of CD antibodies. Please inquire for bulk or custom formulations (without preservative or carrier).
RDI Divison of researchd Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (flow cytometry, neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below. All products are for in vitro research use only-not for use in or on humans or animals-not for use in diagnostics. Price/availability/specifications subject to change without notice.
CD91/LRP Antibodies
Mouse anti-human CD91/LRP antibodies
-2 clones (see other also other lipoprotein abs)
CATALOG# CLONE# Workshop Host Form Price
RDI-PRO61066 5A6 -- mIgG1 purified $375.00
RDI-PRO61067 8B8 " " purified $375.00
Mab to LRP/A2MR(85 kDa)
(low density lipoprotein receptor-related protein/A2-macroglobulin receptor)
cat#RDI-PRO61066 $375.00/vial
Clone 5A6
Category Mouse monoclonal
Form/Purification Protein A affinity purified
Ig Class IgG1
Immunogen Human LRP/A2MR
Clinical Application/
Specificity 5A6 specifically reacts with the 85 kDa BETA-chain of human LRP/a 2MR which is expressed in a re-stricted spectrum of cell types (for a recent review cf. Herz & Strickland). A strong immunohistochemical reaction is seen in hepato-cytes, tissue macrophages, subsets of neurones and astro-cytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in athero-sclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelo-monocytic subtypes of chronic and acute leukemia (CD 91). Neutralizing effects of clone 5A6 Mab has been reported (Basu et al,2001)
Application
FACS analysis
Immunoblotting
Immunohistochemistry
Immunofluorescence
Dilution dilute 1:20 with PBS, pH 7.4 for iimmunohistochemistry
Storage/Stability After reconstitution with 1ml distilled water, the antibody is stable for a min 1 year when stored at 4 DEG C For extended storage keep in aliquots at -20 Deg C. Avoid repeated thawing and freezing.
Quantity: 50ug (lyophilized) contains 0.09% sodium azide 0.5% BSA
Reactivity: human, mouse, rabbit,rat, hamster
References:
-Strickland et al. (1990): J Biol Chem 265, 17401-17404.
-Coukos et al (1994): Am J Pathology 144, 383-392
-Rebeck et al (1993): Neuron 11, 575-580
-Gonias et al (1992): Am J Pathology 141, 37-42
-Strickland DK, Kounnas MZ, Argraves WS (1995): LDL receptor-related protein: a multiligand receptor for lipoprotein and proteinase -catabolism. FASEB J 9:890-898
-Herz J and Strickland DK: LRP, a multifunctional scavanger and signalI ng receptor. J. Clin. Invest. 108, 779-784 (2001)
-Bsu S et al, CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70 and calreticulin. Immunity 14 ,303-313 (2001)141
For research use only, not for therapeutic or diagnostic use!
BULK quotes on request
Mab to LRP/A2MR(85 kDa)
(low density lipoprotein receptor-related protein/A2-macroglobulin receptor)
cat#RDI-PRO61067 $375.00/vial
Clone 8B8
Category Mouse monoclonal
Form/Purification Protein A affinity purified
Ig Class IgG1
Immunogen Human LRP/A2MR
Clinical Application/
Specificity 8B8 specifically reacts with the 85 kDa beta-chain of human LRP/A2MR which is expressed in a restricted spectrum of cell types. A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD91).
Application
FACS analysis
Immunoblotting
Immunohistochemistry
Immunofluorescence
Species: Human,rabbit,rat,hamster,mouse
Dilution dilute 1:20 with PBS, pH 7.4 for iimmunohistochemistry
Storage/Stability After reconstitution with 1ml distilled water, the antibody is stable for a min 1 year when stored at 4 DEG C. For extended storage, reccomned aliquoting and store at -20 DEG C. Avoid frequent freeze thaw cycles.
Quantity: 50ug (lyophilized) contains 0.09% sodium azide 0.5% BSA
References:
Strickland et al (1990): J. Biol. Chem 265, 17401-17404
Couckos et al (1994):Am J. Pathology 144, 383-392.
Rebeck et al (1993): Neuron 11, 575-580
Gonlas et al (1992):Am J Pathology 141, 37-42
Strickland DK et al (1995):FASEB J. 9:890-898
J Clin Invest 108, 779-784 (2001)