rev:   September 1, 2004

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CD CLUSTERED ANTIBODIES  

(anti-Human and others as indicated)

NOTE: Please inquire for bulk or custom formulations (without preservative or carrier).

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (flow cytometry, neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below. All products are for in vitro research use only-not for use in or on humans or animals-not for use in diagnostics. Price/availability/specifications subject to change without notice.

CD68 Antibodies

CATALOG#                 CLONE#                  Workshop    Host         Form        Price

RDI-CD68-82A               Y1/82A                      VI              mIgG2b      purified    $281.00

RDI-CD68-82PE              ""                               IV                 ""             PE            $562.00 100 tests

RDI-CD68abm-KP1         KP1                            --               mIgG         TCS         $500.00/1ml (paraffin sections)

Catalog#: RDI-CD68-82A    $281.00/vial

Package Size: 100ug purified in 0.2ml (0.5mg/ml) 50mM Tris-Hcl (pH 8.0), 0.15M NaCl and 0.1% sodium azide. (sodium azide is toxic, dilute azide compounds with copious amounts of water when disposing in drain to avoid accumulation of explosive deposits- avoid contact with acids.)

Prep: purified

Species: mouse IgG2bk

CLONE: Y1/82A        Workshop Code:VI, MR23

Activity: Reacts with a 110 kd-type I transmembrane glycoprotein expressed in cytoplasmic granules of monocytes/macrophages, dendritic cells, granulocytes, myeloid progenitor cells and, reportedly, a subset of CD34+ hemopoietic bone marrow progenitor cells. CD68 belongs to the sialomucin family and its function has not been fully elucidated.

-tissue localization: expressed strongly in cytoplasmic granules and weakly on the surface of monocytes, macrophages, neutrophils, eosinophils, and a subpopulation of B cells.

Application: -Indirect immunofluorescence cell surface staining (flow cytometry), pos control permeabilzed peripheral blood monocytes

                    -acetone fixed frozen tissue sections


References:

1) Leucocyte Typing VI, Garland Press, NY 1997

2) J. Clin Pathol. 41:753(1988)

3) J. Clin Pathol 89:76 (1988)

Storage: Store at 4 DEG C.

Precautions:For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. It is the esponsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.

suitable for frozen and paraffin sections (paraffin sectiosn require hightemp antigen release with citrate buffer, approx 1:200-1:400 dilution with ABC detection, membrane staining).  Stain macrophages in various tissues including Kupffers cells and in the red pupl of the spleen, laina propia of the gut, lung alveoli and bone marrow. The antibody reacts with myeloid precursors and peripheral blood granulocytes and monocytes.

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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