rev: July 7, 2003
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CD CLUSTERED
ANTIBODIES
(anti-Human and others as indicated)
NOTE:Please inquire for bulk or custom formulations (without preservative or carrier).
RDI Division of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (flow cytometry, neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below. All products are for in vitro research use only-not for use in or on humans or animals-not for use in diagnostics. Price/availability/specifications subject to change without notice.
CD62E
Antibodies
Mouse anti-human CD62E antibodies
-2 clones
RDI-CBL180 1.2B6 V mIgG1 purified $375.00
RDI-CBL180FT " " " " FITC $375.00
RDI-CBL180PE " " " " PE $469.00
RDI-CD62E-382 16G4 --- mIgG TCS $500.00/1ml paraffin
MOUSE ANTI-HUMAN ELAM-1 MONOCLONAL ANTIBODY
PRODUCT CODE :RDI-CBL180 $375.00/vial 200ug
Also available: FITC labeled cat#RDI-CBL180FT $375.00/100 Tests
PE labeled cat#RDI-CBL180PE $469.00/100 Tests
CLONE 1.2B6
ISOTYPE IgG1
IMMUNOGEN TNF-activated human umbilical vein endothelial cells
SOURCE Tissue culture supernatant
PURIFICATION METHOD Protein A affinity chromatography
SPECIFICITY
The antibody is specific to the human antigen E-selectin (ELAM-1, 115 kDa) that is expressed on activated endothelial cells. The ligand is expressed on neutrophils and may function as an early part in neutrophil binding to the endothelium.
APPLICATIONS
*Studies in a wide range of cell interactions in the vasculature together with diagnostic implications
*This antibody works in ELISA, immunohistology (acetone fixed frozne sections) and also inhibits cellular adhesion
KNOWN SPECIES CROSS REACTIVITY Recognizes porcine E-selectin
REFERENCES
Leucocyte Typing Workshop VI, Oxford University Press (1996)
Groves R.W. et al. Br. J. Dermatol. 124 117-123 (1991)
Bevilacqua, M.P. Nelson, R.M. J. Clin Invest 91, 379-87 (1993)
Leucocyte Typing Workshop V. Oxford University Press 2, 1501-3 (1995)
Wellicome, S.M. Thornhill, M.H. Pitzalis, C. Thomas, D.S. Lanchbury, J.S.S.
Panayi, G.S. et al. J. Immunol 144, 2558-65 (1990)
PRESENTATION The monoclonal is presented at a concentration of 200µg/2ml
in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine
serum albumin. We recommend that each laboratory determine an optimum working
titre for use in its particular application.
STORAGE For use within 1 month of purchase store at +4oC, for long term storage
aliquot antibody into small volumes and store at -20oC.
Also available: FITC conjugated cat#RDI-CBL180FT $375.00/100T
PE conjugated cat#RDI-CBL180PE $469.00/100T
Bulk material available (quotes on request)
1 milligram no BSA cat#RDI-CBL180-1X $1125.00/1mg
1 milligram no BSA & NO Azide, cat#RDI-CBL180-1XP $1125.00/1mg
For Research Use Only. Not supplied for use in diagnostic or therapeutic procedures.
34 Junction Square Drive
Concord MA 01742-3049
USA
phone (978) 371-6446 or (800) 370-2222
fax (978) 371-2266
EMAIL:antibodies@fitzgerald-fii.com
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