rev:October 6, 2001

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CD CLUSTERED ANTIBODIES  

(anti-Human and others as indicated)

NOTE: 10% Discount on purchases of  3 or more any combination of CD antibodies. Please inquire for bulk or custom formulations (without preservative or carrier).

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (flow cytometry, neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below. All products are for in vitro research use only-not for use in or on humans or naimals-not for use in diagnostics.

CD1b  Antibodies

Mouse anti-human CD1b ANTIGEN

PRODUCT CODE :RDI-CBL475   $375.00/vial 200ug

    also available: FITC conjugated cat#RDI-CBL475FT     $375.00/vial 100tests

                             PE conjugated cat#RDI-CBL475PE     $469.00/vial 100 tests

CLONE: WM 25

ISOTYPE: IgG1

SOURCE: Mouse ascitic fluid

Antigen: Human thymocytes and splenic lymphocyte

Fusion Partner: NS1 myeloma cell line

PURIFICATION METHOD: DEAE ion exchange chromatography following ammonium sulphate precipitation.

SPECIFICITY: Reacts with an epitope distinct from Human thymocyte antigen-1 (43kDa) expressed on the majority of thymocytes and approximately 50% of cases of T-ALL. This antibody does not stain Langerhans cells.

Antigen distribution: Thymocytes                     80 ± 10%

                              Granulocytes                            < 1%

                              Monocytes                               < 1%

                               B-cells (E+)                             < 1%

                               T-cells (E-)                              < 1%

                               Peripheral blood lymphocytes   < 1%

APPLICATIONS: * Analysis of early stages of T cell differentiation..

                              * Immunodiagnosis of certain acute lymphoblastic leukaemias and high grade T cell non- Hodgkins                                          lymphomas.

                               *Immunoprecipitation studies of CD1b antigen

REFERENCES: Leucocyte Typing IV, Oxford University Press. (1989).

                          Favaloro, E.J. et al. Disease Markers 4, 261 - 70 (1986).

                          Favaloro, E.J. et al. J. Immunol. Cell Biol. 65, 517 - 27 (1987).

                          Favaloro, E.J. Immunol & Cell Bio. 71, 571-81 (1993)

PRESENTATION: Each monoclonal is delivered in a sealed vial at a concentration of 200µg/2ml in phosphate buffered saline solution containing 10mM sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.

STORAGE: Purified monoclonal antibodies are generally stable for long periods at 4oC. However repeated warming to room temperature and re-cooling may result in a loss of activity and hence effective working titre. It is recommended that monoclonal antibodies are aliquotted upon receipt and then stored at -20C. After thawing they should then be used as a stock solution for up to 60 days. Dilute working solutions are best prepared on the day of use.

For research use only. Not supplied for use in human diagnostic or therapeutic procedures

RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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