rev:January 10, 1997
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(anti-Human and others as indicated)
RDI Divison of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
Mouse anti-Na+/K+ alpha 3 subunit Monoclonal
cat# RDI-atpa3abm $406.00/vial
Background: The NA+/K+ Atpase is an integral membrane enzyme found in all
cells of higher organisms and is responsible for the ATP-dependent transport
of NA and K across the cell membrane. The enzyme consists of a large multipass
transmembrane catalytic subunit (alpha subunit) and an associated smaller
glycoprotein (Beta subunit). Studies indicate that there are three isoforms
of the alpha subunit (A1, a2, & A3) and two isoforms of the Beta subunit
(B1 & B2) which are encoded by two multigene families. The alpha
3 subunit has been found in neuronal and to a lesser extent skeletal and
cardiac muscle and lung and stomach tissues.
package: 100ul of diluted ascites fluid with 0.05% sodium azide added
antigen: produced from a fusion of NS-1 myeloma cells and spleen cells from Balb/c mice immunized with canine cardiac microsomes.
Specificity: alpha 3 subunit of NA+/K+ ATPase
-seen in human, rat,
monkey, sheep, canine, rabbit, guinea pig
-Western blot:1ug/ml= recognizes approx 110 kDa band which represents the alpha-3 subunit of the NA+/K+ ATPase.
-Immunohistochemistry: 3ug/ml =stains
consistent with the plasma membrane localization of
Storage: Store at -20 DEG C upon receipt. Avoid frequent freeze thaw cycles. Recommend aliquoting. BEFORE OPENING, suggest centrifuging for 1 minute at 1000 RPM to concentrate material in vial.
Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics.
It is the responsibility of the user to comply with all local/state and Federal
rules in the use of this product. We are not responsible for any patent
infringements that might result with the use of or derivation of this product.
RDI Divison of Fitzgerald Industries Intl
34 Junction Square Drive
Concord MA 01742-3049
phone (800) 370-2222 or (201) 584-7093
fax (978) 371-2266
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