rev:January 10, 1997

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CYTOKERATIN   ANTIBODIES  

(anti-Human and others as indicated)

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


ANTI-CYLICIN I


Mab to Cylicin I  (a basic protein of the sperm head cytoskeleton)

cat#RDI-PRO65142      $281.00/vial


Clone Determination                Cal-144 (X 144.3.2)

Category                                 Mouse monoclonal

Immunoglobulin Subclass        IgM

Purification                             Ascites or hybridoma culture supernatant

Antigen                                 Calyx preparation from bovine sperm (according to Longo et al. 1987, JCB 22, 1105-1120)


Specificity                             Especially useful in discrimination of morphologically altered "round-headed" spermatozoa


Application                           Immunofluorescence microscopy

                                            Immunoblotting (Western)


Polypeptide(s) Reacting        Bovine cylicin I (Mr 74.788, deduced from sequence analysis),

                                            a basic protein (IEP 10.55) of the sperm head cytoskeleton with

                                            Mr 58.000 on SDS-PAGE;  Multiple band proteins with MW 58,

                                           63, 69 and 74 kDa of calyx-associated polypeptides of bovine

                                           spermatozoa;


Antigen Recognized in         Human, bovine

Species (tested so far)


Working Dilution                Ready-to-use for immunofluorescence


Incubation Time                 1 h at RT


Storage                             At 4°C


Volume                             5 ml


References

Hess, H., Heid, H. and Franke, W.W.: Molecular Characterization of Mammalian Cylicin, a Basic Protein of the Sperm Head Cytoskeleton. J. Cell Biol. 5, 1043-1052 (1993)




For research use only. Not supplied for use in human diagnostic or therapeutic procedures


RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (800) 370-2222 or (201) 584-7093

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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