rev: May 14, 2008
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CYTOKERATIN ANTIBODIES
(anti-Human and others as indicated)
RDI Division of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
ANTI-TENASCIN
Mab to Tenascin
cat#RDI-TENASNabm, new cat#: 10R-T103a $412.50/100ug
RDI-TENASNabmX $688.00/200ug
Clone T2H5
Category Mouse monoclonal
Form :purified IgG
Ig Class IgG1
Antigen Isolated from human mammary tumor cells
Introduction Tenascin is a large hexameric extracellular matrix molecule with
oncofetal properties. During embryonic development the protein is expressed in
many parenchymatous organs, where it appears to have a regulating role in
epithelial differentiation. In most mature tissues the expression is restricted
to the papillary dermis, but reappears in tissue regeneration and repair and in
neoplasia. In basal cell carcinoma two forms (Mr 210,000 and 300,000 kDa) of
tenascin can be found, in contrast to normal skin and fibroblasts, where one
form predominantly exists (Mr 300,000 kDa).
Clinical Application/Specificity Detects extracellular matrix glycoprotein
Tenascin in connection with gliomas, mammary tumors and in proliferative skin
diseases (psoriasis, skin tumors)
Recommended for 1: 5 - 1:20
Application :RIA, ELISA
:Immunoblotting (Western)
: Immunohistochemistry
: Suitable for frozen sections
:parrafin sections (with high temperature unmasking)
Antigen Recognized in species tested so far: Human
Working Dilution : 2-4ug/ml
Dilution Buffer PBS (1% BSA and 0.09% Na-Azide)
Incubation Time 1 h at RT
Storage At 4°C
Volume : 100ug
References:
A.A. Verstraeten, E.J. Mackie, Ph.C. Hageman, J. Hilgers, D.J. Schol, G.J. De
Jongh and J. Schalkwijk: Tenascin expression in basal cell carcinoma. British
Journal of Dermatology (1992) 127, 571-574.
Bosman, F.T. et al. Progr Histochem, Cytochem 24(4) 1-92 (1992)
Koukoulis, G.K. et al, Human Pathol., 222,, 636-643 (1991)
For research use only. Not supplied for use in human diagnostic or therapeutic procedures
RDI div of Fitzgerald Industries Intl
(Research Diagnostics Inc)
phone (800) 370-2222
or (978) 371-6446 or (800) 370-2222
fax (978) 371-2266
email: sales@researchd.com
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