rev: May 25, 2005
HOME (index page)
Return (alphabetical antibody page)
Return (cytokeratin data page)
CYTOKERATIN
ANTIBODIES
(anti-Human and others as indicated)
RDI Divison of researchd Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
ANTI-TENASCIN
Mab to Tenascin
cat#RDI-TENASNabm $438.00/100ug
RDI-TENASNabmX $688.00/200ug
Clone T2H5
Category Mouse monoclonal
Form :purified IgG
Ig Class IgG1
Antigen Isolated from human mammary tumor cells
Introduction Tenascin is a large hexameric extracellular matrix molecule
with oncofetal properties. During embryonic development the protein is expressed
in many parenchymatous organs, where it appears to have a regulating role
in epithelial differentiation. In most mature tissues the expression is
restricted to the papillary dermis, but reappears in tissue regeneration
and repair and in neoplasia. In basal cell carcinoma two forms (Mr 210,000
and 300,000 kDa) of tenascin can be found, in contrast to normal skin and
fibroblasts, where one form predominantly exists (Mr 300,000 kDa).
Clinical Application/Specificity Detects extracellular matrix glycoprotein
Tenascin in connection with gliomas, mammary tumors and in proliferative
skin diseases (psoriasis, skin tumors)
Recommended for 1: 5 - 1:20
Application :RIA, ELISA
:Immunoblotting (Western)
: Immunohistochemistry
: Suitable for frozen sections
:parrafin
sections (with high temperature unmasking)
Antigen Recognized in species tested so far: Human
Working Dilution : 2-4ug/ml
Dilution Buffer PBS (1% BSA and 0.09% Na-Azide)
Incubation Time 1 h at RT
Storage At 4°C
Volume : 100ug
References:
A.A. Verstraeten, E.J. Mackie, Ph.C. Hageman, J. Hilgers, D.J. Schol, G.J.
De Jongh and J. Schalkwijk: Tenascin expression in basal cell carcinoma.
British Journal of Dermatology (1992) 127, 571-574.
Bosman, F.T. et al. Progr Histochem, Cytochem 24(4) 1-92 (1992)
Koukoulis, G.K. et al, Human Pathol., 222,, 636-643 (1991)
For research use only. Not supplied for use in human diagnostic or therapeutic procedures
RDI div of researchd Industries Intl
(Research Diagnostics Inc)
San Jose, 95123 CA Snell ave 658
USA
phone 408-780-0908
or (978) 371-6446 or 408-780-0908
fax 408-780-0908
email: sales@researchd.com
RETURN(cytokeratin page)