rev: 5/15/2008

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CYTOKERATIN   ANTIBODIES  

(anti-Human and others as indicated)

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


ANTI-CYTOKERATIN  4


Mab to Cytokeratin 4

cat#RDI-PRO10525, new cat#: 10R-C169a   $484.00/vial
 

Clone Determination 6B10


Category Mouse monoclonal, culture supernatant


IgG Class IgG1


Antigen Isolated From Human oesophagus


Clinical Application/ Specificity 6B10 recognizes cytokeratin 4 in non-cornifying squamous epithelia. Cytokeratin 4 is mostly present in combination with cytokeratin 13. In contrast to cytokeratin 13, the superficial cells of the cornea are reactive with cytokeratin 4. 6B10 also stains ciliated pseudo-stratified epithelium of bronchi and, focally, ductal epithelial cells.

Recommended Positive Control for :Squamous cell carcinomas

Application Suitable for:

             Immunohistochemistry of frozen tissue and cell suspensions

             Immunoblotting

Polypeptide Reacting: 59 kD cytokeratin 4


Antigen Recognized in Species (tested so far) human, most mammals

Working Dilution 1:5 - 1:10


Dilution Buffer PBS with 1% BSA and 0.1% Na-Azide


Incubation Time 1 h at room temperature


Storage At 4°C (undiluted) or at -20°C (aliquots)


Volume 1 ml

ref: Muijen GNP van, et al, Cell Type Heterogenity of Cytokeratin epithelia and Carcinomas as Demonstrated by monoclonal antibodies specfic for cytokeratins nos. 4 and 13. Exp Cell Res 162:97-113(1986)

For research use only. Not supplied for use in human diagnostic or therapeutic procedures


RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (800) 370-2222 or (201) 584-7093

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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