rev: November 3, 2003
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CYTOKERATIN &
RELATED
ANTIBODIES
(anti-Human and others as indicated)
RDI Divison of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
TALIN C-terminal (see also anti-Talin clone TA205)
CLONE: TD77
ISOTYPE: IgG1
SOURCE: Tissue culture supernatant
PURIFICATION METHOD: Protein A affinity chromatography.
SPECIFICITY: Reacts with the C terminal end of talin ( a a 2269-2541) which
also contains an F-catin binding site homologous to the yeast actin binding
protein SLA2p.
APPLICATIONS: * Studies into the role of talin as a part of the intracellular
matrix its co-association with vinculin and its overall role as a G-action
binding protein.
-the antibody also cross reactis with mouse and chicken
REFERENCES: Bolton, S.J. et al Cell Moltility and the Cytokeratin 36, 363-76
(1997)
PRESENTATION: Each monoclonal is delivered at a concentration of 200ug/2ml
in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine
serim albumin. We recommend that each laboratory determine an optimum working
titre for use in its particular application.
STORAGE: Purified monoclonal antibodies are generally stable for long periods at 4oC. However repeated warming to room temperature and re-cooling may result in a loss of activity and hence effective working titre. It is recommended that monoclonal antibodies are aliquotted upon receipt and then stored at -200C. After thawing they should then be used as a stock solution for up to 60 days. Dilute working solutions are best prepared on the day of use Avoid frequent freeze thaw cycles.
For research use only. Not supplied for use in human diagnostic or therapeutic procedures
34 Junction Square Drive
Concord MA 01742-3049
USA
phone (978) 371-6446 or (800) 370-2222
fax (978) 371-2266
EMAIL:antibodies@fitzgerald-fii.com
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