rev: September 8, 1998

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CYTOKERATIN   ANTIBODIES  

(anti-Human and others as indicated)

RDI Divison of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


ANTI-CYTOKERATIN  1-3


MOUSE MONOCLONAL  ANTIBODY TO: HUMAN CYTOKERATIN 1-3

PRODUCT CODE   RDI-CBL222    $375.00/vial 200ug

CLONE         AE8

ISOTYPE      IgG1

SOURCE     Mouse ascitic fluid

PURIFICATION METHOD   Ion exchange chromatography followed by ammonium sulphate precipitation

SPECIFICITY   This antibody recognizes human cytokeratin 1-3. Cytokeratin 1-3 is expressed by several stratified squamous epithelia such as vagina, tongue, oral mucosa, oesophagus, epidermis and urothelium of bladder and squamous cell carcinomas such as cervical carcinomas and transitional cell carcinoma of bladder

APPLICATIONS

*Identification of cytokeratin 1-3 expressing tissues by indirect immunofluorescence staining or by indirect immunoperoxidase staining of frozen sections

*CBL222 is excellent for identifying various forms of squamous metaplasia and cell type heterogenety

REFERENCES

Sun, T-T. et al. Cancer Cell 1, 169-76 (1984)

Cooper, D. et al. Lab. Invest. 52, 243-56 (1985)

PRESENTATION The monoclonal is presented at a concentration of 200µg @ 1mg/ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.

STORAGE For use within 1 month of purchase store at +4oC, for long term storage aliquot antibody into small volumes and store at -20oC.

For research use only. Not supplied for use in human diagnostic or therapeutic procedures


RDI Divison of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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