rev: February 22, 1999
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(anti-Human and others as indicated)
RDI Divison of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
PRODUCT CODE RDI-CBL208 $469.00/vial
IMMUNIZING ANTIGEN Electrophoretically purified cytokeratin 20 from human intestinal mucosa
SOURCE Mouse ascitic fluid
PURIFICATION METHOD Hydrophobic interaction chromatography
SPECIFICITY The antibody is specific for the 46 kDa polypeptide (cytokeratin 20). It represents an excellent marker for certain carcinomas such as adenocarcinoma of the colon, transitional cell carcinoma of the bladder and Merkel cell skin tumours. The antibody can be used in the detection of intestinal and gastric foveolar epithelium, urothelial cells and Merkel cells of the epidermis as well as tumours of their origin (eg. primary and metastatic colorectal cancer).
Adenocarcinomas of the breast and lung also neuroendocrine tumours of the
lung are essentially negative.
*Suitable for staining paraffin wax embedded tissue following enzyme digestion and incubation for 1 hour at room temperature
Moll, R. et al. J. Cell Biol. 111, 567-580 (1990)
Moll, I. & Moll, R. Arch. Dermatol. Res. 283, 300-309 (1991)
Moll, R. et al. Am. J. Path. 140, 427-447 (1992)
LOT SPECIFIC DATAPRESENTATION The monoclonal is presented as 50µg of lyophilysed material (contains 0.5% BSA and 0.09% NaN3). Reconstitute with 1ml distilled water. The working dilution is 5µg/ml but we recommend that each laboratory determine an optimum working titre for use in its particular application.
STORAGE For use within 1 month of purchase store at +4oC, for long term storage aliquot antibody into small volumes and store at -20oC.
-see also rec human cytokeratin 20 antigen
For research use only. Not supplied for use in human diagnostic or therapeutic procedures
RDI Divison of Fitzgerald Industries Intl
34 Junction Square Drive
Concord MA 01742-3049
phone (978) 371-6446 or (800) 370-2222
fax (978) 371-2266