rev: September 8, 1998

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CYTOKERATIN   ANTIBODIES  

(anti-Human and others as indicated)

RDI Divison of researchd Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.

ANTI-CYTOKERATIN  TYPE 13

MOUSE MONOCLONAL ANTIBODY TO: HUMAN CYTOKERATIN 13

 PRODUCT CODE   RDI-PRO61007    $375.00/vial

CLONE        Ks 13.1

ISOTYPE     IgG1

IMMUNIZING ANTIGEN   Cytokeratin 13 purified from human oesophagus

SOURCE    Mouse ascitic fluid

PURIFICATION METHOD    Protein A affinity chromatography

SPECIFICITY   This antibody reacts with human cytokeratin 13 with minor affinity for cytokeratins 14 and 17. Cytokeratin 13 (54 kDa) is expressed by several stratified squamous epithelia such as vagina, tongue, oral mucosa, oesophagus, epidermis and urothelium of bladder. Squamous cell carcinomas such as cervical carcinomas, cloacogenic carcinomas and transitional cell carcinoma of bladder also express cytokeratin 13.

APPLICATIONS

*Identification of cytokeratin 13 expressing tissues by indirect immunofluorescence staining or by indirect immunoperoxidase staining of frozen sections

*Identification of cytokeratin 13 expressing tissues in formalin fixed wax embedded tissue sections by immunohistochemistry

* excellent for identifying various forms of squamous metaplasia and cell type heterogeneity

*Western blotting

KNOWN SPECIES  CROSS REACTIVITY      Recognizes bovine and rat

REFERENCES

Franke, W. W. et al. Viral Etiology of Cervical Cancer 121-148, Cold Spring Harbour Lab. (1986)

Moll, R. et al. AM. J. Path. 132, 123-44 (1988)

Moll, R. et al. Cell 31, 11-24 (1982)

PRESENTATION The monoclonal is presented as 50µg of lyophilysed material. Reconstitute with 1ml distilled water. We recommend that each laboratory determine an optimum working titre for use in its particular application.


STORAGE For use within 1 month of purchase store at +4oC, for long term storage aliquot antibody into small volumes and store at -20oC.


For research use only. Not supplied for use in human diagnostic or therapeutic procedures

RDI Divison of researchd Industries Intl

San Jose, 95123 CA Snell ave 658

USA

or 408-780-0908

EMAIL:margaret@cellular-research.com

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