rev: September 8, 1998
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CYTOKERATIN
ANTIBODIES
(anti-Human and others as indicated)
RDI Divison of researchd Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
ANTI-CYTOKERATIN TYPE 13
PRODUCT CODE RDI-PRO61007 $375.00/vial
CLONE Ks 13.1
ISOTYPE IgG1
IMMUNIZING ANTIGEN Cytokeratin 13 purified from human oesophagus
SOURCE Mouse ascitic fluid
PURIFICATION METHOD Protein A affinity chromatography
SPECIFICITY This antibody reacts with human cytokeratin 13 with minor affinity for cytokeratins 14 and 17. Cytokeratin 13 (54 kDa) is expressed by several stratified squamous epithelia such as vagina, tongue, oral mucosa, oesophagus, epidermis and urothelium of bladder. Squamous cell carcinomas such as cervical carcinomas, cloacogenic carcinomas and transitional cell carcinoma of bladder also express cytokeratin 13.
APPLICATIONS
*Identification of cytokeratin 13 expressing tissues by indirect immunofluorescence staining or by indirect immunoperoxidase staining of frozen sections
*Identification of cytokeratin 13 expressing tissues in formalin fixed wax embedded tissue sections by immunohistochemistry
* excellent for identifying various forms of squamous metaplasia and cell type heterogeneity
*Western blotting
KNOWN SPECIES CROSS REACTIVITY Recognizes bovine and rat
REFERENCES
Franke, W. W. et al. Viral Etiology of Cervical Cancer 121-148, Cold Spring Harbour Lab. (1986)
Moll, R. et al. AM. J. Path. 132, 123-44 (1988)
Moll, R. et al. Cell 31, 11-24 (1982)
PRESENTATION The monoclonal is presented as 50µg of lyophilysed material.
Reconstitute with 1ml distilled water. We recommend that each laboratory
determine an optimum working titre for use in its particular
application.
STORAGE For use within 1 month of purchase store at +4oC, for long term storage
aliquot antibody into small volumes and store at -20oC.
For research use only. Not supplied for use in human diagnostic or therapeutic
procedures
RDI Divison of researchd Industries Intl
San Jose, 95123 CA Snell ave 658
USA
or 408-780-0908
EMAIL:margaret@cellular-research.com
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