rev:     January 11, 2004

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ANTIBODIES  

(anti-Human and others as indicated)

RDI Divison of researchd Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


Mouse anti-Calnexin Monoclonal ab

cat# RDI-CALNEXabm       $438.00/vial 50ug

      RDI-CALNEXabm-1     $750.00/vial 150ug


Background: Calnexin is a 90kDa integral; membrane protein located primarily in the E domain. It contains a long N-terminal calcium binding domain extending into the lumen of the E, with a short acidic cytosolic domain. Calnexin associates with several cell surface binding proteins as they pass through the E. Since it also forms complexes with other resident E proteins involved in the CA2+ dependent retention of proteins, calnexin may act as a chaperone. The amino acid sequence of calnexin is highly conserved among species and similar in sequence to calreticulin, a major calcium binding protein found in the E. Neither calnexin nor calreticulin contain the calcium-binding motif, known as the "E-F hand", found in the calmodulin family of proteins.

isotype: mIgG1


package: 50ug (200ul) or 150ug (600ul) (at 0.25mg/ml in 50% glycerol, PBS + 1.5mM NaN3 & 1mg/ml BSA)


antigen: N-terminal protein fragment corresponding to amino acids 116-301 of human calnexin. (in calcium binding region)

USE: Suitable for western blot on human, dog, and rat using approx 0.25-1 ug/ml ab on total cell of HELA cells. Major band =MW 90kDa.


Storage: Store at -20 DEG C upon receipt. Recommend aliquoting. Avoid frequent warming cycles.


Main REF: -Tjoelker, L.W. et al, 1993:Biochemistry


Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


RDI Divison of researchd Industries Intl

San Jose, 95123 CA Snell ave 658

USA

or (800) 370-2222

EMAIL:margaret@cellular-research.com

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