rev: October 23, 2001
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Anti-RAT
CD CLUSTERED
ANTIBODIES
RDI Division of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (flow cytometry, neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below. All products are for in vitro research use only-not for use in or on humans or animals-not for use in diagnostics. Price/availability/specifications subject to change without notice.
Anti-RAT CD62L (L-Selectin/LECAM-1)
Antibodies
Catalog#: RDI-RTCD62L-H1 (Discontinued) $281.00/1pkg
$219.00/package 5+
Package Size: 0.1mg in 0.2ml 10mM Phosphate buffer, pH 7.2 with 150mM NACL
and 0.09% sodium azide
Clone: HRL1
Ig Isotype: armenian hamster IgG group 2g
Immunogen: Rat Lecam-1 human IgG1 fusion protein
Reactivity: Reacts with rat L-selectin, which is detected on a small percentage
of thymocytes and on most neutrophils and peripheral lymphocytes. CD62L is a
90kDa receptor with lectin-like and epidermal growth factor-like domains, which
binds to sialylated oligosaccaride determinats on high endothelial venules
(HEV) in peripheral lymph nodes. This member of the selectin adhesion molecule
family appears to be required for lymphocyte homing to peripheral lymph nodes
and to contribute to neutrophil emigration at inflammatory sites. Expression of
L-selectinb on lymphocytes and neutrophils is rapidly down-regulated upon cell
activation, and on the level of antigen expression distinguishes naive CD4+ T
cells from effector/memory T helper cells. Clone HRL1 Mab inhibits the ligand
binding activity of L-selectin in invitro assays and slows in vivo leukocyte
rolling on microvascular endothelium.
USE: flow cytometry(<1ug/1M cells) using EDTA as an antigcoagulant (heparin
should not be used).
-function blocking (azide free)
ref: -Eur. J. Immunol 23:2181-2188
-J. Immunol 152:832-840
Storage: Store at 4 DEG C
Precautions:For In vitro research Use Only. Not for use in or on humans or
animals or for diagnostics.
also available: Biotin labeled cat#RDI-RTCD62L-H1BT
$562.00/0.5mg
FITC labeled cat#RDI-RTCD62L-H1FT $594.00/0.5mg
Catalog#: RDI-RTCD62L-H2 (Discontinued) $281.00/1pkg
Package Size: 0.1mg in 0.2 TRIS with 0.09% sodium azide
Clone: HRL2
Ig Isotype: armenian hamster IgG group 1k
Immunogen: Rat Lecam-1 human IgG1 fusion protein
Reactivity: Reacts with rat L-selectin, which is detected on a small percentage
of thymocytes and on most neutrophils and peripheral lymphocytes. CD62L is a
90kDa receptor with lectin-like and epidermal growth factor-like domains, which
binds to sialylated oligosaccaride determinats on high endothelial venules
(HEV) in peripheral lymph nodes. This member of the selectin adhesion molecule
family appears to be required for lymphocyte homing to peripheral lymph nodes
and to contribute to neutrophil emigration at inflammatory sites. Expression of
L-selectinb on lymphocytes and neutrophils is rapidly down-regulated upon cell
activation, and on the level of antigen expression distinguishes naive CD4+ T
cells from effector/memory T helper cells. Clone HRL2 Mab recognizes a
different epitope from that recognized by clone HRLL1 and DOES NOT INHIBIT the
ligand binding activity of L- selectin.|
USE: flow cytometry(<1ug/1M cells) using EDTA as an antigcoagulant (heparin
should not be used).
-histochemistry (acetone fixed frozen sections 1-5ug/ml)
-ELISA
ref: -Eur. J. Immunol 23:2181-2188
-J. Immunol 152:832-840
Storage: Store at 4 DEG C
Precautions:For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics.
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fax (978) 371-2266