rev: June 18, 2004
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Anti-RAT
CD CLUSTERED
ANTIBODIES
RDI Division of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (flow cytometry, neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below. All products are for in vitro research use only-not for use in or on humans or animals-not for use in diagnostics. Price/availability/specifications subject to change without notice.
Anti-RAT CD
42D Antibodies
Catalog#: RDI-rtCD42D-M4 Price: $500.00/1pkg 0.5mg
also available FITC conj cat#RDi-RTCD42D-4FT $406.00/100ug
Supplied: Purified form: 0.5mg in 1ml (0.5mg/ml) 10mM phosphate buffer pH7.2
with 150mM NaCl and 0.09% sodium azide.
Clone: RPM.4
Immunogen: Wistar Rat Platelets
Ig Isotype: mouse (BALB/C) IgG2ak
Purification: Purified from TCS by affinity chromatography
Reactivity: Clone RPM.4 Mab reacts with CD42d (Platelet glycoprotein V, GPV),
an 88-kDa glycoprotein which noncovalently associates with GPIb and GPIX
to form a receptor for von Willebrand factor on megakaryocytes and resting
platelets. The binding sites for von Willebrand factor and thrombin have
been localized to the GPIb chain of the GPIb-V-IX complex. GPV is cleaved
by thrombin to release a 70-kDa soluble fragment, which contains the epitope
recognized by mAb RPM.4. 1 Although the rat CD42d protein’s structure
is similar to that of human CD42d, the RPM.4 antibody does not cross-react
with human platelets.
USE: -flow cytometry(<1ug/1M cells)
-immunoprecipitation
-not recommended for western blot
ref: -Ravanet, C. et al. 1997. Blood 89: 3253 3262.
Storage: Store at 4 Deg C.
Precautions: For In vitro research Use Only. Not for use in or on humans
or animals or for diagnostics. Sodium azide may form explosive compounds
in presence of heavy metals or under acidic conditions. Flush drains with
copious amounts of water to prevent buildup of explosive compounds.
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RDI Division of Fitzgerald Industries Intl
34 Junction Square Drive
Concord MA 01742-3049
USA
phone (978) 371-6446 or (800) 370-2222
fax (978) 371-2266
EMAIL:antibodies@fitzgerald-fii.com