rev:    Ocotber 4,  2001

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Anti-RAT
CD CLUSTERED ANTIBODIES  

RDI Divison of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (flow cytometry, neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below. All products are for in vitro research use only-not for use in or on humans or animals-not for use in diagnostics. Price/availability/specifications subject to change without notice.


Anti-RAT  CD13 Antibodies



MOUSE MONOCLONAL ANTIBODY TO: HUMAN CD13 (also reacts with rat)

PRODUCT CODE    RDI-CBL169   $438.00/vial

CLONE    WM 15

ISOTYPE   IgG1

SOURCE   Mouse ascitic fluid

PURIFICATION METHOD   Ion exchange chromatography

SPECIFICITY

The CD13 antigen is present on many non-haemopoietic tissues and represents an integral single chain membrane glycoprotein of 150 kDa. Present on monocytes and weakly expressed on granulocytes, it is only present on a small proportion of normal bone marrow cells. These comprise a major portion of the normal granulocyte-macrophage progenitor population. CD13 is a type III glycoprotein, the extracellular region of which contains the catalytic unit of aminopeptidase-N which is a zinc binding metalloprotease.


APPLICATIONS

*Phenotyping of leukaemias

*Immunoprecipitation studies of the CD13 moiety

*This antibody may be used to deplete plasma of its aminopeptidase-N activity since the plasma enzyme may be the soluble form of membrane derived CD13

*Studies of serum alanine aminopeptidase in hepatobiliary disease since the enzyme is an isoform of the CD13 antigen

KNOWN SPECIES CROSS REACTIVITY     Recognizes rat

REFERENCES

Leucocyte Typing III, Oxford University Press (1987)

Leucocyte Typing IV, Oxford University Press (1989)

Bradstock, K. F. et al. Br. J. Haem. 61, 11-20 (1985)

Favaloro, E. J. et al. Clin. Chim. Acta 220, 81-90 (1993)

Favaloro, E. J. et al. Exp. Haematol. 21, 1695-1701 (1993)

LOT SPECIFIC DATA

PRESENTATION The monoclonal is presented at a concentration of 200µg/2ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.

STORAGE For use within 1 month of purchase store at +4oC, for long term storage aliquot antibody into small volumes and store at -20oC.

Also available: FITC labeled cat#RDI-CBL169FT $395.00/100T

RPE-CY5 cat#RDI-CBL169PC5 $500.00/100T

See other anti-human CD antibodies a t: http://www.researchd.com/rdicdabs/cdindex.htm

For Research Use Only. Not supplied for use in diagnostic or therapeutic procedures.


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RDI Divison of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com