rev: Ocotber 4, 2001
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Anti-RAT
CD CLUSTERED
ANTIBODIES
RDI Division of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (flow cytometry, neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below. All products are for in vitro research use only-not for use in or on humans or animals-not for use in diagnostics. Price/availability/specifications subject to change without notice.
Anti-RAT CD13 Antibodies
PRODUCT CODE RDI-CBL169 $438.00/vial - DISCONTINUED
CLONE WM 15
ISOTYPE IgG1
SOURCE Mouse ascitic fluid
PURIFICATION METHOD Ion exchange chromatography
SPECIFICITY
The CD13 antigen is present on many non-haemopoietic tissues and represents an
integral single chain membrane glycoprotein of 150 kDa. Present on monocytes
and weakly expressed on granulocytes, it is only present on a small proportion
of normal bone marrow cells. These comprise a major portion of the normal
granulocyte-macrophage progenitor population. CD13 is a type III glycoprotein,
the extracellular region of which contains the catalytic unit of
aminopeptidase-N which is a zinc binding metalloprotease.
APPLICATIONS
*Phenotyping of leukaemias
*Immunoprecipitation studies of the CD13 moiety
*This antibody may be used to deplete plasma of its aminopeptidase-N activity since the plasma enzyme may be the soluble form of membrane derived CD13
*Studies of serum alanine aminopeptidase in hepatobiliary disease since the enzyme is an isoform of the CD13 antigen
KNOWN SPECIES CROSS REACTIVITY Recognizes rat
REFERENCES
Leucocyte Typing III, Oxford University Press (1987)
Leucocyte Typing IV, Oxford University Press (1989)
Bradstock, K. F. et al. Br. J. Haem. 61, 11-20 (1985)
Favaloro, E. J. et al. Clin. Chim. Acta 220, 81-90 (1993)
Favaloro, E. J. et al. Exp. Haematol. 21, 1695-1701 (1993)
LOT SPECIFIC DATA
PRESENTATION The monoclonal is presented at a concentration of 200µg/2ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.
STORAGE For use within 1 month of purchase store at +4oC, for long term storage aliquot antibody into small volumes and store at -20oC.
Also available: RPE-CY5 cat#RDI-CBL169PC5 $500.00/100T
See other anti-human CD antibodies a t: http://www.researchd.com/rdicdabs/cdindex.htm
For Research Use Only. Not supplied for use in diagnostic or therapeutic procedures.
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RDI Division of Fitzgerald Industries Intl
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Concord MA 01742-3049
USA
phone (978) 371-6446 or (800) 370-2222
fax (978) 371-2266