rev: February 2, 2005
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Anti-MOUSE
CD CLUSTERED
ANTIBODIES
RDI Division of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (flow cytometry, neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below. All products are for in vitro research use only-not for use in or on humans or animals-not for use in diagnostics. Price/availability/specifications subject to change without notice.
Anti-MOUSE CD49b
Antibodies
DATA SHEET:Hamster anti mouse CDw49b (Integrin alpha 2 chain monoclonal )
Catalog#: RDI-MCD49B-HMA2 $469.00/0.5mg
no azide/sterile filtered # RDI-MCD49B-HMAP $625.00/0.5mg
FITC conjugated: # RDI-MCD49B-HMFT $375.00/100ug
Package Size: 0.5mg purified ab in Tris-Hcl with 0.1%NaN3
Clone: HMA2
Ig Isotype: armenian Hamster IgG
Purification: Purified from ascites
Reactivity: Reacts with CD49B, the 150kDa transmembrane glycoprotein that
non- covalently associates with the integrin B1 subunit (CD29) to form the
integrin A2B1 complex known as VLA-2, which is a receptor for collagen and
lamminin. VLA-2 is expressed on some splenic cells, CD4+ T lymphocytes, on
intestinal intraepithelial and lamina proporia lymhocytes, NK cells, epithelial
cells and platelets, BUT NOT on thymocytes, nor Peyers patch, peripheral
lymph node, nor mesenteric lymph node lymphocytes. The expression of VLA-2
is up-regulated on lymphocytes in responses to mitogens. Clone HMA2 has been
reported to partially block the interaction of T cell blasts but not
NK cells, with collagen. Purified HMA2 Mab blocks the staining of splenic
NK cells byu the anti-CD49B/Pan-NK cells mab DX5..
USE: flow cytometry(<1ug/1M cells)
histochemistry (acetone fixed frozen sections)
immunoprecipitation
blocking (azide free material)
ref: Eur J. Immunol 24:2000-2005 (1994)
Int Immunol. 7:1183-1189 (1995)
Intl Immunol 167:1141-1144
Storage: Store at 4 DEG C
Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. Sodium azide may form explosive compounds in presence of heavy metals or under acidic conditions. Flush drains with copious amounts of water to prevent buildup of explosive compounds.
DATA SHEET: Hamster IgG, group 1, kappa Isotype Control (No Azide,
sterile filtered)
Catalog#: RDI-HAMIGG1K-X $375.00/vial
Package Size: 500 ug purified IGG, group 1 kappa in 0.5 ml of 10mm PBS pH
7.2 and 150mM NaCl. NO preservative or carrier protein added. Sterile filtered.
Endotoxin <0.01ng/ug of ab at time of packaging.
Species: hamster IgG, group 1, kappa (armenian)
Clone: A19-3
Immunogen: TNP-KLH
Activity: -specific for the hapten trinitrophenol (TNP) and selected as an
isotype control following screening for low background on a variety of mouse
spleen and bone marrow suspensions.
Application: -negative control for hamster IgG group 1K, kappa (Aremenian
hamster) isotype neutralizing antibodies
-flow cytomtery
Storage: Store at 4 DEG C immediatley upon arrival. Aliquot and avoid frequent
warming cycles. Handle under asceptic conditions Precautions: For In vitro
research Use Only. Not for use in or on humans or animals or
for diagnostics. Animal use requires approval of animal welfare
committee.
It is the responsibility of the user to comply with all local/state and Federal
rules in the use of this product. We are not responsible for any patent
infringements that might result with the use of or derivation of this products.
inquire for formulations with azide or conjugates
34 Junction Square Drive
Concord MA 01742-3049
USA
phone (978) 371-6446 or (800) 370-2222
fax (978) 371-2266
EMAIL:antibodies@fitzgerald-fii.com