rev: October 8, 2003
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Anti-MOUSE
CD CLUSTERED
ANTIBODIES
RDI Division of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (flow cytometry, neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below. All products are for in vitro research use only-not for use in or on humans or animals-not for use in diagnostics. Price/availability/specifications subject to change without notice.
Anti-MOUSE CD47
Antibodies
Catalog#: RDI-MCD47-301 $500.00/0.5mg
RDI-MCD47-301FT $625.00/0.5mg (fitc conjugated)
Package Size: 0.5mg in 1ml (0.5mg/ml) Purified immunoglobulin in 10 mM phosphate
buffer, pH 7.2 with 150 mM NaCl and 0.09% (w/v) sodium azide.
Clone: mipa301
Ig Isotype: rat IgG2ak
Immunogen: not specified
Reactivity: Clone miap301 Mab reacts with the extracellular domain of CD47,
also known as Integrin-Associated Protein (IAP).1 CD47 is a 50-kDa plasma
membrane protein with an extracellular immunoglobulin variable region-like
domain, a multiple membrane-spanning segment, and a short C-terminal cytoplasmic
tail.2 IAP is often physically associated with B3 integrins, and it may act
as a transducer element in activation mediated by these integrins.1,2,3 CD47
is expressed by a wide variety of cell types, including some cells lacking
integrins, such as erythrocytes.1,3 The cytoplasmic tail region is expressed
as alternatively spliced forms, which are differentially expressed in diverse
tissues, suggesting that IAP may have distinct functions in various tissues.3
USE:
-flow cytometry(<1ug/1M cell
-acetone fixed frozen section (histochemistry)
-western blot
ref: 1. Science 274: 795 - 798.
2. J. Cell Biol. 123: 485 - 496.
3. J. Cell Sci. 108: 3419 - 3425.
Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. Sodium azide may form explosive compounds in presence of heavy metals or under acidic conditions. Flush drains with copious amounts of water to prevent buildup of explosive compounds. RDI is not be responsible for violations or patent infringements which may occur with the use of or derivation of our products.
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RDI Division of Fitzgerald Industries Intl
34 Junction Square Drive
Concord MA 01742-3049
USA
phone (978) 371-6446 or (800) 370-2222
fax (978) 371-2266
EMAIL:antibodies@fitzgerald-fii.com