rev: March 3, 1998

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(anti-Human and others as indicated)

RDI Divison of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.

ANTI-snRNP 70 kD
Mab to snRNP 70 kD Protein (human Autoantigen)

Cat#RDI-PRO61050    $562.00

Clone Determination H 111

Category Mouse monoclonal

Immunoglobulin Class IgG2a

Purification Ammonium sulphate precipitation

Antigen for Immunization Purified snRNPs from HeLa cells

Specificity H 111 specifically recognizes the U1 70 kD protein in many species including human and mouse. The antibody reacts with human anti- RNP sera in immunoblotting. H111 precipitates U1 snRNP complexes containing the U1 70K protein.

Antigen Recognized in Human, mouse

Application Dot blot or immunoblotting, Immunoprecipitation

Storage Lyophilized at 2-8°C

Solution: three months at 2-8°C or in aliquots at -20°C aliquots at -20 Do not freeze solution

Working Dilution When reconstituted with 1 ml distilled water, dilute further 1:10 for dot blot and immunoblotting

Quantity 1 ml (lyoph.)

References Reuter, R. and Lührmann, R.: Immunization of mice with purified U1 small nuclear ribonucleoprotein (RNP) induces a pattern of antibody specificities characteristic of the anti-SM and anti-RNP autoimmune response of patients with lupus erythematosus, as measured by monoclonal antibodies. Proc. Natl. Acad. Sci. USA, 8689-8693 (1986).

For Research Use Only

RDI Divison of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049


phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

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