rev: March 3, 1998
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(anti-Human and others as indicated)
RDI Divison of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
Clone Determination H 111
Category Mouse monoclonal
Immunoglobulin Class IgG2a
Purification Ammonium sulphate precipitation
Antigen for Immunization Purified snRNPs from HeLa cells
Specificity H 111 specifically recognizes the U1 70 kD protein in many species including human and mouse. The antibody reacts with human anti- RNP sera in immunoblotting. H111 precipitates U1 snRNP complexes containing the U1 70K protein.
Antigen Recognized in Human, mouse
Application Dot blot or immunoblotting, Immunoprecipitation
Storage Lyophilized at 2-8°C
Solution: three months at 2-8°C or in aliquots at -20°C aliquots at -20 Do not freeze solution
Working Dilution When reconstituted with 1 ml distilled water, dilute further 1:10 for dot blot and immunoblotting
Quantity 1 ml (lyoph.)
References Reuter, R. and Lührmann, R.: Immunization of mice with purified U1 small nuclear ribonucleoprotein (RNP) induces a pattern of antibody specificities characteristic of the anti-SM and anti-RNP autoimmune response of patients with lupus erythematosus, as measured by monoclonal antibodies. Proc. Natl. Acad. Sci. USA, 8689-8693 (1986).
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