rev:   April 3, 2005

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  ANTIBODIES  

(anti-Human and others as indicated)

RDI Divison of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


Melanocortin Receptor Antibodies
Polyclonal Anti-Melanocortin Receptor atibodies

MC1-R, MC2-R, MC3-R, MC-4R and MC5-R

-The melanocotrin family comprises the alpha, beta, and gamma-melanocyte stimulating hormones (MSH) and adreocorticotrophin. The receptors for these hormones are seven transmembrane G protein coupled proteins that adenyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC3-R is the ACTH receptor and is expressed in the adrenal cortex. MC3-R and MC4-R are expressed primarily in brain while MC5-R is expressed in low levels in most tissues.


rabbit anti-MC1R (human/mosue/rat, sheep)

cat#RDI-MC1Rabr    $500.00/100ug

-made against a 21aa cytoplamsic domain epitope from mouse

-homology with human (15/21 aa 71%), horse (14/21aa 66%), bovine (14/21aa, 66%), sheep (14/21, 66%) and Red fox (12/60, 60%)

-corss reactivity not established with other species

-control peptide cat#RDI-MC1R-CP $188.00/100ug


rabbit anti-MC2R (mouse,human/hamster/bovine)

cat#RDI-MC2Rabr   $500.00/100ug

-made against a 17aa cytoplamsic domain epitope from mouse

-homology with human (12/17 aa 71%), bovine (13/17, 76%),

-corss reactivity not established with other species

-control peptide cat#RDI-MC2R-CP   $188.00/100ug  


rabbit anti-MC3-R (mouse/rat/human)

cat#RDI-MC3RCabr   $469.00/100ug

-made against 18 amino acids in cytoplasmic domain (mouse and rat)

-homology with rat (15/18, 83%) human-recommend cat#RDI-MC3REabr

-corss reactivity not established with other species

-control peptide cat#RDI-MC3RC-CP $188.00/100ug


rabbit anti-MC3R (human)

cat#RDI-MC3REabr    $500.00/100ug

-made against a 18aa extracellular domain epitope from human

-homology with moue (11/18, 61%)-for mouse use above

-corss reactivity not established with other species

-control peptide cat#RDI-MC3RE-CP   $188.00/100ug  


rabbit anti-MC4R (human)

cat#RDI-MC4Rabr   $500.00/100ug

-made against a 14aa cytoplamsic domain epitope from human

-homology with monkey, pig & bovine (100%), mouse (84%), rat (69%)

-corss reactivity not established with other species

-control peptide cat#RDI-MC4R-CP $188.00/100ug


rabbit anti-MC4R (rat)

cat#RDI-RTMC4Rabr    $500.00/100ug

-made against a 18aa N terminal extracellular epitope from rat

-homology with human ,monkey (16/18 aa 88%), 76% with pig, 78% with bovine, 64% with chicken

-corss reactivity not established with other species

-control peptide cat#RDI-RTMCR4R-CP $188.00/100ug


rabbit anti-MC5R (mouse/rat/human)

cat#RDI-MC5Rabr   $500.00/100ug

-made against a 15aa extracellular domain epitope from mouse

-homology with rat (14/15aa, 93%) human (14/15 aa 93%), hamster and bovine (11/15, 73%)

-corss reactivity not established with other species

-control peptide cat#RDI-MC5R-CP $188.00/100ug


For In Vitro Research Use Only

RDI Divison of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

email: sales@researchd.com

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