rev: December 9, 2004
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(anti-Human and others as indicated)
RDI Divison of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
Catalog#: RDI-MANNOSRabm $281.00/vial
also available: azide free.0.2micron filtered cat#RDI-CD206-19XP $750.00/0.5mg
PE: cat#RDI-MANNOSR-PE $500.00/100 tests with 0.09% NaN3
FITC: cat#RDI-CD206-19FT $469.00/100T with 0.09% NaN3
Package Size: 100ug in 0.2ml (0.5mg/ml) buffer with 0.09% NaN3.
Species: mouse IgG1k
Purification: purified by Protein G from tissue culture supernatant
Activity: Reacts with the macrophage mannose receptor (MR), a membrane glycoprotein of approx 162kD which binds to glycoconjugates containing mannose, fructose or N-acetylglucosamine. these carbohydrates are present on the surface of many microorganisms and enable the MR to bind to microorganisms and internalize them during the process of phagocytosis. Mannose receptors are expressed on human macrophages and cultured dendritic cells. They are not detected on resting monocytes. Mannose receptor expression is upregulated on PBMC following 24hr incubation with GM-CSF.
Application: -Indirect fluorescence (approx 1ug/1M cells) (tested on GM-CSF stimulated for 3 days with PBMN cells )
-histochemistry on acetone fixed frozen sections (not tested on paraffin)
-titers must be determined for each application
Storage: Store at 4 Deg C.
References: -International review of Cytology 37:221
also available labeled with PE: cat#RDI-MANNOSR-PE $500.00/100tests
Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.
-see also mannose-6-phosphate receptor monoclonal and Human Mannose Binding Lectin Elisa cat#RDI-M1990clb $688.00
RDI Divison of Fitzgerald Industries Intl
34 Junction Square Drive
Concord MA 01742-3049
phone (800) 370-2222
or (978) 371-6446 or (800) 370-2222
fax (978) 371-2266
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