rev: May 27, 2001

HOME (index page)

Return (master antibody page)

Return  (alphabetical antibody.index)


  ANTIBODIES  

(anti-Human and others as indicated)

RDI Divison of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


MOUSE MONOCLONAL ANTIBODY TO: HUMAN CALGRANULIN A

PRODUCT CODE             RDI-CBL269          $375.00

CLONE                            CF-145

ISOTYPE                          IgG2b

SOURCE                          Mouse ascitic fluid

PURIFICATION METHOD

                                     Ion-exchange chromatography

SPECIFICITY       The antibody recognizes calgranulin A (S100 calcium-bindingProtein A8) which is expressed by macrophages in chronic inflammation. It is also found in granulocytes and in subset ofnormal stratified squamous epithelia including tongue,oesophagus and buccal cells. Calgranulin is found in elevatedlevels in the serum of cystic fibrosis cases and is also expressed in the skin of patients with psoriasis,eczematous dermatitis, some GVDH and squamous cell carcinoma.

APPLICATIONS * The antibody is suitable for use on formalin fixed paraffin sections where it may be seen as a marker for reactive epthelium in skin and for skin squamous cell carcinomas.* Flow cytometry.* ELISA assay.

REFERENCES Dorin J.R. et al. (1990) Genomics 8: 420-426.Dorin J.R. et al .(1987 Nature 326 (6133): 614-617Van Heyningen V. et al. (1985), Nature 315 (6019) 513-515Wilkinson M.M. et al. (1988) J. Cell Science 91:221-230

PRESENTATION The monoclonal is presented at a concentration of 200µg/2ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.

STORAGE For use within 1 month of purchase store at +4oC, for long term storage aliquot antibody into small volumes and store at -20oC.


Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics.  It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


RDI Divison of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA USA

phone (800) 370-2222

      or (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

Return  (alphabetical antibody.index)

Ordering terms