rev:    February 13, 2005

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  ANTIBODIES  

(anti-Human and others as indicated)

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.

see 2 clones below

Apolipoprotein A5 (ApoA5) is fast gaining attention as a key  reg lator of ser m triglyceride concentrations. An ApoA5  mouse knock-out model produced an approximately four fold  increase in serum triglycerides, whereas a knock-in model with h man ApoA5 prod ced 50–70% lower concentrations of mo se ser m triglycerides. In addition, peroxisome proliferator-activated receptor-4 (PPAR-a) agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in hu man serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.

Mouse anti-ApoA5     see also pdf file  apoa5abm-e2.pdf

cat#RDI-APOA5abm-E2  $562.00/100ug

-clone ref#4H8H8E2

-mIgG1

-immunogen: Ni-NTA purified full length recombinant human APOA5 expressed in E Coli strain BL21 (DE3)

-western blot: 1:2000-1:5K

-Elisa

ref:1. Pennacchio, L. et al. Science 2001 294, 169-173

      2. Prie r, X. et al. (2003) J Biol Chem 278, 25468-25480

      3. Obrien, PJ. et al. (2005) Clin Chem 51:2, 1-9

Mouse anti-ApoA5  see also pdf file  apoa5abm-g9.pdf

cat#RDI-APOA5abm-G9   $562.00/100ug

clone ref#1G5G9

-mIgG1

-immunogen:Ni-NTA purified truncated recombinant human APOA5 expressed in E Coli strain BL21 (DE3)

-use: western blot (1:500-1K)

         Elisa

ref: 1. Pennacchio, L. et al. Science 2001 294, 169-173

      2. Prie r, X. et al. (2003) J Biol Chem 278, 25468-25480

      3. Obrien, PJ. et al. (2005) Clin Chem 51:2, 1-9

For research use only, not for therapeutic or diagnostic use!

RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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