rev: December 5, 2003
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ANTIBODIES
(anti-Human and others as indicated)
RDI Divison of researchd Industries Intl offers a wide line of antibodies. Since
no one antibody works best for all applications (neutralization, blotting,
histochemistry, ELISA, etc), we offer many different types of antibodies
to help solve this problem. Please inquire for other applications or types
of antibodies not listed below.
Cat
No:
RDI-8OHGUANabG
$315.00/0.25ml
Clone:
Polyclonal
-ELISA using
immunizing peptide: 1:250,000
-IHC using formalin-fixed,
paraffin-embedded sections: 1:200
-IHC using paraformaldehyde-fixed,
frozen sections: N/D
-Western blots:
N/A
Preservative:
0.1% Sodium
Azide
~
Storage:
Short term: Refrigerate at
4º
C
Long term:
Freeze at
-20º
C.
FOR RESEARCH AND MANUFACTURING USE ONLY
8OHdG has become increasing popular as a sensitive, stable and integral marker of oxidative damage in cellular DNA. Biomonitoring in humans has demonstrated that 8OHdG can be excreted in the urine, and that a significant increase is caused by exposure to tobacco smoke and ionizing radiation. Because 8OHdG is so well correlated with oxidative stress and damage to DNA, which leads to degenerative disease states, the development of an antibody that can be used to study DNA damage has numerous applications. In addition to the direct study of DNA damage within cells, this antibody has applications in the development of immunoassays that can monitor 8OHdG excretion in the urine and serve as a biomarker of oxidative stress. Industrial uses may extend to the dietary supplement manufacturers, who could benefit from an immunoassay that could be used to test the effectiveness of antioxidants and other neutraceuticals.
Alzheimer disease brain
showing immunohistochemcal
![]() |
Competitive ELISA using
the 8-OHG antibody demonstrates
For Research Use Only-Not For Use in
Diagnostics
RDI Divison of researchd Industries Intl
San Jose, 95123 CA Snell ave 658
USA
or 408-780-0908
EMAIL:margaret@cellular-research.com
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