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ANTIBODIES
(anti-Human and others as indicated)
RDI Divison of Fitzgerald Industries Intl offers a wide line of antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.
ANTI-Desmocollin 2 (see below 2 polyclonals)
(see also desmocollin 1 & 3 antibodies)
Rabbit Pab to Desmocollin 2
Cat#RDI-PRO610120 $375.00
Source Rabbit
Form Whole antiserum
Antigen Extracellular part of human Desmocollin 2 (recombinant)
Reactive Polypeptide Desmocollin 2a and 2b (splice forms; mw 78 535,
corresponding to 712 amino acids)
Antigen Recognized in Human, bovine
Species (tested so far)
Localization All desmosome-possessing cell types, including epithelia, myocardiac cells and lymph nodes and neoplasia derived therefrom
Application Suitable for · immunohistochemistry on frozen* and paraffin-
embedded** (P) tissue
· cytological material
· immunoblotting*** (Western)
Working Dilution * 1:100 for immunohistochemistry
** 1:50 for paraffin-embedded tissue
*** 1:2000
for Western blotting
Incubation Time 1 h at RT;
extended with P
Storage At 2-8°C
Volume 100 µl; contains 0.09% sodium azide
For research use only, not for therapeutic or diagnostic use!
References
1. Nuber UA, Schäfer S, Stehr S, Schmidt A, Koch PJ, and Franke WW: The widespread human desmocollin DSC2 and tissue-specific patterns of synthesis of various desmocollin subtypes. Eur. J. Cell Biol. 66, 69-74 (1995).
2. Moll I, Houdek P, Schäfer S, Nuber U, and Moll R: Diversity of desmosomal proteins in regenerating epidermis: Immunohistochemical study using a human skin organ culture model. Arch. Dermatol. Res. 291, 437-446 (1999).
For Research Use Only
Cat#RDI-PROGP542 $438.00
Source Guinea pig
Form Whole antiserum
Antigen Extracellular part of human Desmocollin 2 (recombinant)
Reactive Polypeptide Desmocollin 2a and 2b (splice forms; mw 78 535,
corresponding to 712 amino acids)
Antigen Recognized in Human, bovine
Species (tested so far)
Localization All desmosome-possessing cell types, including epithelia, myocardiac cells and
lymph nodes and neoplasia derived therefrom
Application Suitable for: · immunohistochemistry on frozen* and paraffin-embedded** (P) tissue
· cytological material
· immunoblotting*** (Western)
Working Dilution * 1:100 for immunohistochemistry
** 1:50 for paraffin-embedded tissue
*** 1:2000 for Western blotting
Incubation Time 1 h at RT; extended with P
Storage At 2-8°C
Volume 100 µl; contains 0.09% sodium azide
For research use only, not for therapeutic or diagnostic use!
References
1. Nuber UA, Schäfer S, Stehr S, Schmidt A, Koch PJ, and Franke WW: The widespread human desmocollin DSC2 and tissue-specific patterns of synthesis of various desmocollin subtypes. Eur. J. Cell Biol. 66, 69-74 (1995).
2. Kurzen H, Moll I, Moll R, Schäfer S, Simics E, Amagai M, Wheelock M, and Franke WW: Compositionally different desmosomes in the various compartments of the human hair follicle. Differentiation 63, 295-304 (1998).
RDI Divison of Fitzgerald Industries Intl
34 Junction Square Drive
Concord MA 01742-3049
USA
phone (978) 371-6446 or (800) 370-2222
fax (978) 371-2266
EMAIL:antibodies@fitzgerald-fii.com
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