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  ANTIBODIES  

(anti-Human and others as indicated)

RDI Divison of researchd Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.

ANTI-Desmocollin 2 (see below 2 polyclonals)

 (see also desmocollin 1 & 3 antibodies)

Rabbit Pab to Desmocollin 2

Cat#RDI-PRO610120  $375.00

Source                          Rabbit

Form                            Whole antiserum

Antigen                         Extracellular part of human Desmocollin 2 (recombinant)

Reactive Polypeptide    Desmocollin 2a and 2b (splice forms; mw 78 535,

                                      corresponding to 712 amino acids)

Antigen Recognized in    Human, bovine

Species (tested so far)

Localization                      All desmosome-possessing cell types, including epithelia, myocardiac cells and lymph nodes and neoplasia derived therefrom

Application Suitable for    · immunohistochemistry on frozen* and paraffin-

                                            embedded** (P) tissue

                                          · cytological material

                                          · immunoblotting*** (Western)

Working Dilution            * 1:100 for immunohistochemistry

                                       ** 1:50 for paraffin-embedded tissue

                                        *** 1:2000 for Western blotting

Incubation Time               1 h at RT; extended with P

Storage At 2-8°C

Volume 100 µl; contains 0.09% sodium azide

For research use only, not for therapeutic or diagnostic use!

References

1. Nuber UA, Schäfer S, Stehr S, Schmidt A, Koch PJ, and Franke WW: The widespread human desmocollin DSC2 and tissue-specific patterns of synthesis of various desmocollin subtypes. Eur. J. Cell Biol. 66, 69-74 (1995).

2. Moll I, Houdek P, Schäfer S, Nuber U, and Moll R: Diversity of desmosomal proteins in regenerating epidermis: Immunohistochemical study using a human skin organ culture model. Arch. Dermatol. Res. 291, 437-446 (1999).

For Research Use Only

Cat#RDI-PROGP542     $438.00

Source                                Guinea pig

Form                                   Whole antiserum

Antigen                                Extracellular part of human Desmocollin 2 (recombinant)

Reactive Polypeptide         Desmocollin 2a and 2b (splice forms; mw 78 535,

                                           corresponding to 712 amino acids)

Antigen Recognized in      Human, bovine

Species (tested so far)

Localization                      All desmosome-possessing cell types, including epithelia, myocardiac cells and

                                          lymph nodes and neoplasia derived therefrom

Application Suitable for: · immunohistochemistry on frozen* and paraffin-embedded** (P) tissue

                                         · cytological material

                                         · immunoblotting*** (Western)

Working Dilution            * 1:100 for immunohistochemistry

                                      ** 1:50 for paraffin-embedded tissue

                                      *** 1:2000 for Western blotting

Incubation Time            1 h at RT; extended with P

Storage At 2-8°C

Volume 100 µl; contains 0.09% sodium azide

For research use only, not for therapeutic or diagnostic use!

References

1. Nuber UA, Schäfer S, Stehr S, Schmidt A, Koch PJ, and Franke WW: The widespread human desmocollin DSC2 and tissue-specific patterns of synthesis of various desmocollin subtypes. Eur. J. Cell Biol. 66, 69-74 (1995).

2. Kurzen H, Moll I, Moll R, Schäfer S, Simics E, Amagai M, Wheelock M, and Franke WW: Compositionally different desmosomes in the various compartments of the human hair follicle. Differentiation 63, 295-304 (1998).

RDI Divison of researchd Industries Intl

San Jose, 95123 CA Snell ave 658

USA

or 408-780-0908

EMAIL:margaret@cellular-research.com

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