rev:  November 23, 2000

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ANTIBODIES  

(anti-Human and others as indicated)

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.

Catalog#: RDI-HLADR-G46   $281.00/vial

Package Size: 100ug purified antibody in Tris   buffer w/0.1%NaN3

    or azide free for blocking cat#RDI-HLADR-G46XP   $938.00/0.5mg

   (sterile filtered, endotoxin tested)

Species: mouse

Isotype: mIgG2ak

clone: G46-6 ( or L243)

Reactivity: -reacts with HLA-DR,   This antibody blocks MLR

Uses: -immunofluorescent staining

          -flow cytometry

         -stimulation inhibition assays (azide free)

         -acetone fixed frozen sections

ref: -PNAS 76(12):6552, 1979

Storage: Store at 4 DEG C. For extensive dilutions, add protein containing or stabilizing medium.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. Sodium azide may form explosive compounds in presence of heavy metals or under acidic conditions. Flush drains with copious amounts of water to prevent buildup of explosive compounds.

Also available: Fitc conjugated cat#RDI-HLADR-G4639FT $438.00/vial 100 tests

Catalog#: RDI-HLA2-TU39  $281.00/vial

Package Size: 100ug purified antibody in Tris buffer w/0.1%NaN3

or azide free for blocking cat#RDI-HLA2-TU39XP $938.00/0.5mg

    sterile filtered, endotoxin tested

Species: mouse

Isotype: mIgG2ak

clone: Tu39

Reactivity: -reacts with a common epitope expressed by all major histocompatibility CLASS II HLA-DR and DP antigens and most DQ antigens expressed on B Cells, macrophages and activated T cells. This antibody fixes complement and blocks MLR

Uses: -immunofluorescent staining

         -flow cytometry

         -stimulation inhibition assays

ref: -Human Immunol 12:165

      -Immunobiol 171:77.

Storage: Store at 4 DEG C. For extensive dilutions, add protein containing or stabilizing medium.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. Sodium azide may form explosive compounds in presence of heavy metals or under acidic conditions. Flush drains with copious amounts of water to prevent buildup of explosive compounds.

Also available: Fitc conjugated cat#RDI-HLA2-TU39FT $438.00/vial 100 tests

DATA SHEET:    Mouse anti-Human HLA-DR

Catalog#: RDI-HLADR-TU36   $281.00/vial

Package Size: 100ug purified antibody in Tris buffer w/0.1%NaN3

Species: mouse

Isotype: mIgG2b

clone: Tu36

Reactivity: -reacts with a monomorphic epitope of major histocompatability Class II HLA-DR antigens expressed on B cells, activated T cells, and antigen presenting cells Detects the alphaB complex and not the isolated chains.This antibody fixes complement.

Uses: -immunofluorescent staining

         -flow cytometry

        -stimulation inhibition assay

ref: -Human Immunol 12:165

     -Immunobiol 171:77.

Storage: Store at 4 DEG C. For extensive dilutions, add protein containing or stabilizing medium.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. Sodium azide may form explosive compounds in presence of heavy metals or under acidic conditions. Flush drains with copious amounts of water to prevent buildup of explosive compounds.

Also available: Fitc conjugated cat#RDI-HLADR-TU36FT $438.00/vial 100 tests

DATA SHEET:    Mouse anti-Human HLA-DQ

Catalog#: RDI-HLADQ-TU169   $281.00/vial

Package Size: 100ug purified antibody in Tris buffer w/0.1%NaN3

Species: mouse

Isotype: mIgG2a

clone: Tu169

Reactivity: -reacts with a major histocompatability CLASS II HLA-DQ1 and DQ2 antigens and weakly with HLA-DQ3. HLA-DQ is expressed primarily on immunocompetent B cells and also on macrophages. This antibody does not cross-react with HLA-DR2 or DR7. This antibody fixes complement.

Uses: -immunofluorescent staining

         -flow cytometry

ref: -Barclay, N.A. et al 1993:The Leucocyte Facts Book. Academic Press, p372.

Storage: Store at 4 DEG C. For extensive dilutions, add protein containing or stabilizing medium.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. Sodium azide may form explosive compounds in presence of heavy metals or under acidic conditions. Flush drains with copious amounts of water to prevent buildup of explosive compounds.

Also available: Fitc conjugated cat#RDI-HLADQ-TU169FT $438.00/vial 100 tests

Catalog#: RDI-HLADM   $312.00/vial

Package Size: 100ug purified antibody in 0.2ml (0.5mg/ml) Tris buffer w/0.09% NaN3

Species: mouse

Isotype: mIgG1k

clone: MaP.DM1

Reactivity: Reacts with Hhuman leukocyte antigen DM (HLA-DM), a non classical MHC class II molecule expressed in thecytoplasm of antigen presenting cells (APC). HLA-DM is composed of alpha abeta subnits which form a similar structure as the classical class II molecules. HLA-DM catalyzes the dissociation of CLIP from MHC class II-CLIP complexes in vitro and facilitates the binding of antigenic peptides. It also prevents self-antigens from becoming stably comlexed with class II molecules and being presented to T cells.

Uses: --flow cytometry

           - acetone fixed frozen sections

ref: Immunity 1:595 (1994)

       J Cell Biol 125:1225 (1994)

        Cell 82:155 (1995)

Storage: Store at 4 DEG C. For extensive dilutions, add protein containing or stabilizing medium.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. Sodium azide may form explosive compounds in presence of heavy metals or under acidic conditions. Flush drains with copious amounts of water to prevent buildup of explosive compounds.

Also available:

PE conjugated cat#RDI-HLADM-PE   $500.00/vial 100T

see also antibodies to human CLIP and HLA-DO

RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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