rev: November 23, 2000

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ANTIBODIES  

(anti-Human and others as indicated)

RDI Divison of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


DATA SHEET: Mouse anti-Human HLA-DM

Catalog#: RDI-HLADM   $312.00/vial

Package Size: 100ug purified antibody in 0.2ml (0.5mg/ml) Tris buffer w/0.09% NaN3

Species: mouse

Isotype: mIgG1k

clone: MaP.DM1

Reactivity: Reacts with Hhuman leukocyte antigen DM (HLA-DM), a non classical MHC class II molecule expressed in thecytoplasm of antigen presenting cells (APC). HLA-DM is composed of alpha abeta subnits which form a similar structure as the classical class II molecules. HLA-DM catalyzes the dissociation of CLIP from MHC class II-CLIP complexes in vitro and facilitates the binding of antigenic peptides. It also prevents self-antigens from becoming stably comlexed with class II molecules and being presented to T cells.

Uses: --flow cytometry

        -acetone fixed frozen sections


ref: Immunity 1:595 (1994)

       J Cell Biol 125:1225 (1994)

      Cell 82:155 (1995)


Storage: Store at 4 DEG C. For extensive dilutions, add protein containing or stabilizing medium.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. Sodium azide may form explosive compounds in presence of heavy metals or under acidic conditions. Flush drains with copious amounts of water to prevent buildup of explosive compounds.

Also available:

PE conjugated cat#RDI-HLADM-PE $500.00/vial 100T

see also antibodies to human CLIP and HLA-DO


FOR RESEARCH USE ONLY. NOT FOR DIAGNOSTIC USE.


RDI Divison of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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