rev: March 6, 2000

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ANTIBODIES  

(anti-Human and others as indicated)

RDI Divison of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


Mouse ANTI-Human HLA CLASS II ANTIGEN (DR)

PRODUCT CODE :RDI-CBL120                     $375..00/vial 200ug

CLONE                TAL.1B5

ISOTYPE             IgG1

IMMUNOGEN    33 kDa alpha-chain subunit of HLA-D products prepared from the lymphoblastoid cell line Bristol 8.

SOURCE             Tissue culture supernatant

PURIFICATION

METHOD            Protein A affinity chromatography

SPECIFICITY This antibody is specific for the alpha chain of monomorphic HLA-DR Class II antigen. This antibody reacts with B cells, activated T cells, macrophages, antigen presenting cells, e.g. Langerhans' cells of skin, interdigitating reticulum cells as well as some endothelial and epithelial tissues.The antibody also detects Class ll antigens which may be expressed 'de novo' or increased in certain pathological states, e.g. autoimmune diseases. Similarly, it will demonstrate aberrant expression of Class ll antigen in various malignant cell types.

APPLICATIONS * HLA typing* Works on formalin fixed, paraffin wax embedded sections and frozen sections

REFERENCES9809 Adams, T. E. Immunol 50, 613-624 (1983)Crumpton, M.J. et. al. Histocompatibility Testing, Berlin: Springer-Verlag 29-37 (1984)

PRESENTATION The monoclonal is presented at a concentration of 200µg/2ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.

STORAGE For use within 1 month of purchase store at +4oC, for long term storage aliquot antibody into small volumes and store at -20oC.

Bulk Quotes Upon Request

Also available: FITC labeled cat#RDI-CBL120FT $375.00/100T

                          PE labeled cat#RDI-CBL120PE $469.00/100TFor Research Use Only. Not supplied for use in diagnostic or therapeutic procedures

For Research Use Only. Not supplied for use in diagnostic or the


RDI Divison of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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