rev:  5/16/2008

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INSULIN  RELATED ANTIBODIES  

(anti-Human and others as indicated)

RDI Division of Fitzgerald Industries Intl  offers a wide line of  antibodies. Since no one antibody works best for all applications (neutralization, blotting, histochemistry, ELISA, etc), we offer many different types of antibodies to help solve this problem. Please inquire for other applications or types of antibodies not listed below.


Mouse anti-Insulin Receptor Beta   (Human/Mouse/rat) clone CT-3  NEW

-cat#RDI-INSRBabm-C3, new cat#: 10R-I137b      $484.00/100ug

-clone CT-3, mIgG1

-western blot, histochemistry, affinity purification with peptide elution, Elisa capture(order without BSA cat#RDI-INSRBabm-C3X $500.00/100ug BSA free)

-recognizes 95Kda B subunit of insulin receptor. Directed against C terminus and does not cross react with IGF-1 receptors.


Mouse anti-Insulin Receptor Beta   (Human/Mouse/rat)   clone CT-1 N  EW

-cat#RDI-INSRBabm-C1, new cat#: 10R-I137a    $484.00/100ug

-clone CT-1, mIgG1

-excellent for IP of murine insulin receptor, western blot (clone CT-3 better), histochemistry, affinity purification with peptide elution, Elisa capture(order without BSA cat#RDI-INSRBabm-C1X $500.00/100ug BSA free), tyrosine kinase assay (with ab mediated capture on microtiter plates, use BSA free formulation).

-recognizes 95Kda B subunit of insulin receptor. Epitope between aa - GRVLTLPRS within the c-terminal of intracellular portion of human insulin receptor B-subunit. Phosphorylation of the threonine residue within this sequence (corresponding to the known phosphorylation site thr-1348 in the insulin receptor( decreases binding by approx 100 fold. Reacts with autophosphorylated and unoccupied receptors as well as the receptor-insulin complex. This clone does not effect insulin-stimulated autophosphorylation. -ref: Biochemical Journal, 1992, 288:195-205.


Mouse anti-Insulin Receptor Beta (Huma n) clone 18-44 NEW

-cat#RDI-INSRBabm-44    $438.00/100ug    $625.00/200ug BULK QUOTES ON REQUEST

-clone 18-44, mIgG2b

-human reactive, does not react with mouse,rat,cow, pig, sheep or rabbit -excellent for IP of human insulin receptor, insulin like agonsit (order BSA and azide free cat#RDI-INSRBabm-44XP $500.00/100ug

-recognizes 95Kda B subunit of insulin receptor. Epitope at exon 12, aa 765- 770 extracellular region.

-ref: Biochemical Journal, 1986, 235(1):199-208, Biochemical Journal, 1987, 242(1):123-9



RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax     (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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