rev: 5/16/2008

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Sample Kit Protocol: (see actual insert with kit for batch specific information):


Pelikine Compact Tool -Kit


CAT# RDI-M1980clb, new cat#: 55R-M1980clb 288 tests    PRICE: $242.00


Itroduction:

The Pelikine Tool set has been developed to complement CLB's successful line of Pelikine Compact Elisa kits. The latter have been designed to combine the ease of a ready-to-use kit with the economy of a do-it-yourself assay. Thus, the user of our Pelikine Compact kits only has to make a few simple buffer solutions and Elisa reagents. The Pelikine Tool set contains the chemicals and solutions to be used in the Pelikine Compact kits: coating and washing buffers, as well as substrate and stop solutions. Now you are certain of high-quality solutions, to obtain optimal Elisa  results and by using these ready-made components, you save time and prevent mistakes as well.

The Pelikine Tool set: to make most out of your CLB Pelikine Compact Elisa kits!

II. Storage and Stability:

The Pelikine Tool set should be stored at 2-8'C. The performanceof the kit is guaranteed until the expiration date shown on the bag label.


III. Contents of the Set:

The Pelikine Tool set contains material sufficient for one Pelikine compact kit (288 tests), reagents provided are:


Quantity                   Component                                 Amount

1 bottle                       coating buffer capsules                  3 pcs for 3 x 100 ml buffer

1 bottle                       PBS tablets                                  3 pcs for 3 x 200 ml buffer

2 bottles                      Washing buffer                             2 x 50 ml 20-fold concentrated

1 bottle                        TMB substrate solution                40 ml ready-for-use

1 bottle                        Stop solution (0.18M H2SO4)     40 ml ready-for-use

 

IV. Precautions For Use

1) The Pelikine Tool set is intended for research purposes only.

2) Only use the reagents supplied with the set, do not mix re agents from different kit lots.

3) Do not add any preservative to the supplied reagents, they may have direct or indirect effects on the final colour develop ment of the HRP-substrate system.

4) The washing buffer contains thiomersal (0.001% w/v) and may be toxic upon ingestion, inhalation or skin contact. Avoid con tact of skin, eyes or clothing with dilution, washing or substrate buffer. In case of contact, wash skin or eyes with water and consult a physician.

5) Avoid any skin or eye contact with TMB substrate solution or stop solution provided with this set. In case of contact,wash skin or eyes with water and consult a physician.

6) Do not expose the TMB substrate solution to strong light during incubation or storage. The TMB substrate solution must be colourless when used; if the solution turns blue, it must be replaced.

7) TMB substrate solution or stop solution should not be in contact with metals or metal ions, 10 avoid unwanted colour formation.


V. Additional Materials Required:

- Distilled or deionized water.

- Beakers, flasks,cylinders necessary for preparation (and storage)of prepared buffers.


VI. Preparation of Buffers:

Coating buffer:

Dissolve the contents of one capsule in 100 ml of distilled water. Wait for 5 minutes, mix contents and the working- strength coating buffer is ready for use.

The prepared buffer can be stored in a closed container up to one week at 2-8'C.

Bring buffer to room temperature (18-25'C) and apply buffer as described in your Pelikine compact kit insert.

PBS solution:

Dissolve one tablet in 200 ml of distilled water.Wait for 5 minutes, mix contents and the working-strength phosphate buffered saline (PBS) solution is ready for use.

The prepared buffer can be stored in a closed container up to one week at 2-8'C.

Bring buffer to room temperature (18-25'C) and apply buffer as described in your Pelikine compact kit insert.

Wash buffer:

Prepare a working-strength solution by adding 50 ml of the wash buffer concentration (total content of the bottle) to 950 ml distilled water. The working-strength solution wash buffer can be stored up to 2 months at 2-8'C.

Bring buffer to room temperature (18-25'C) and apply buffer as described in your Pelikine compact kit insert.

 

VII. Substrate and Stop Solutions:

TMB substrate solution

The supplied substrate solution is a ready-for-use mixture of 3, 3',5,5'-tetramethylbenzidine (TMB) and hydrogen peroxide.Protect substrate solution from prolonged exposure to light.

Bring TMB substrate solution to room temperature (18-25'C) and apply as described in your Pelikine compact kit insert.

Stop solution:

The supplied stop solution is a ready-for-use sulphuric acid solution (0.18M) in water.

Bring stop solution to room temperature (18-25'C) and apply as described in your Pelikine compact kit insert.



VIII. Material Safety Data Sheet:

Hazardous Ingredients

3,3',5,5'-Tetramethylbenzidine may be harmful inhalation, ingestion, or skin absorption. May cause irritation. To our best knowledge the chemical, physical and toxicological properties have not been thoroughly investigated. CAS No. 54827-17-7.


Thiomersal may be toxic upon ingestion, inhalation or skin contact. Avoid contact of skin, eyes or clothing with dilution, washing or substrate buffer. In case of contact, wash skin or eyes with water and consult a physician. CAS No. 54-64-8


Sulphuric Acid: 0.18 M H2SO4 in water. In case of contact, wash skin or eyes with water and consult a physician. CAS No. 7664-93-9.


Physical data

No information is available on physical data for the chemical mixture as a whole.


Health hazard

Please refer to "Precautions for use", page 1 of this information leaflet.


Protection information

Please refer to "Precautions for use", page 1 of this information leaflet.


Disclaimer

The above information is believed to be accurate and represents the best information available to us. However, CLB neither warrants the accuracy of this information nor assumes any legal responsibility in connection with its dissemination. All material and mixtures may present unknown hazards and should be used with caution. Users should make their own investigations to determine the suitability of this information for their particular purpose.

For In Vitro Research Use Only-Not for use in Diagnostics


RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax      (978) 371-2266

EMAIL:antibodies@fitzgerald-fii.com

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