rev April 13, 2000

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Murine/Rat Cytokine/Growth Factor/Chemokines Sample Spec sheets (subject to change without notice):


DATA SHEET:recombinant RAT Interleukin 1 ALPHA)

Rat Interleukin 1 alpha (rtIL-1A) is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses including the activation of B and T cells. This recombinant Rat IL-1A is a 18 kDa protein containing 156amino acid residues.

Catalog#: RDI-RTIL1A-AG or RDI-RTIL1A-AGX (NO BSA)

Package Size: 5 micrograms $469.00        25micrograms $1062.00

Supplied: Lyophilized protein from sterile filtered PBS containing 50ug of bovine serum albumin per ug of IL1A (if desired without carrier, add -X to catalog number) .

Source: E. Coli

Purity: >97% by SDS-Page analysis and visualized by silver stain. Endotoxin level is less than 0.1ng per ug of rat IL-1A.

Reconstitution: The lyophilized IL-1A is soluble in water and most aqueous buffers. The lyophilized powder should be reconstituted in sterile PBS to a concentration of no less than 1ug/ml. Allow to set at least 30 minutes, rotate and mix well. Centrifuge for 1-2 minutes at 1000RPM to concentrate solution in bottom of vial. This solution can be diluted into water or other buffered solutions and store under sterile conditions at 4 DEG C for up to one month or aliquot and store at -20 DEG C for future use.

Note:if using the carrier free material and this material is not to be used for coating or labeling (or other applications requiring carrier free material), the addition of 0.1% BSA to dilution buffers or dilution in sterile culture media is recommended to enhance stability and minimize absorption to vial. Ideally, maintain stock >1ug/ml.

Storage: The lyophilized powder, though stable at room temperature, is best stored desiccated below 0 DEG C. reconstituted rat IL-1A should be stored in working aliquots at -20 DEG C. Avoid Frequent Freeze- THAW Cycles.

Reactivity: The ED50 as determined by the dose dependent stimulation of murine helper T cell line D10.G4.1 cells is 3-7pg/ml.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals   or for diagnostics.  It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


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