rev:    December 14, 2004

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Murine/Rat Cytokine/Growth Factor/Chemokines Sample Spec sheets (subject to change without notice):


DATA SHEET:recombinant Mouse RELM-ALPHA

-RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha re still unknown. This recombinant murine RELM-alpha is a 10.0 kDa monomeric protein containing 88 amino acid residues.

Catalog#: RDI-4526

Package Size: 25 micrograms $231.00    $219.00/package 2+

                      MINI-PACK:cat#RDI-4526P $94.00/5ug


Supplied: The sterile filtered solution was lyophilized from 10 mM   Tris, pH 7.5 + 25 mM NaCl.

Source: E. Coli

Purity: Greater than 97% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Reconstitution: We recommend a quick spin followed by reconstitution in 10mM Tris pH7.4 or sterile DI water to a concentration of 0.1-1.0 mg/ml. Allow to set at least 30 minutes at 4 DEG C, tighten cap and rotate to reconstitute any material on sides of vial. If desired, you can centrifuge at 1000 rpm for 1 minute to concentrate volume in bottom of vial. This solution can be diluted into other buffered solutions containing carrier protein or medium containing serum and stored at 4 DEG C (up to 1 week) or -20 DEG C long term)

Storage: The lyophilized powder is stable at room temperature for a few weeks but it is best stored desiccated at -20 Deg C. Reconstituted RELM-ALPHA should be stored in working aliquots at -20 DEG C . AVOID FREQUENT FREEZE THAW CYCLES.

Reactivity: not determined

AA Sequence:

MDETIEIIVE NKVKELLANP ANYPSTVTKT LSCTSVKTMN RWASCPAGMT

ATGCACGFAC GSWEIQSGDT CNCLCLLVDW TTARCCQLS

For In vitro research Use Only. Not for use in or onhumans or animals or for diagnostics.  It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


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