rev:    December 14, 2004


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Murine/Rat Cytokine/Growth Factor/Chemokines Sample Spec sheets (subject to change without notice):

DATA SHEET:recombinant Mouse RELM-ALPHA

-RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha re still unknown. This recombinant murine RELM-alpha is a 10.0 kDa monomeric protein containing 88 amino acid residues.

Catalog#: RDI-4526

Package Size: 25 micrograms $231.00    $219.00/package 2+

                      MINI-PACK:cat#RDI-4526P $94.00/5ug

Supplied: The sterile filtered solution was lyophilized from 10 mM   Tris, pH 7.5 + 25 mM NaCl.

Source: E. Coli

Purity: Greater than 97% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Reconstitution: We recommend a quick spin followed by reconstitution in 10mM Tris pH7.4 or sterile DI water to a concentration of 0.1-1.0 mg/ml. Allow to set at least 30 minutes at 4 DEG C, tighten cap and rotate to reconstitute any material on sides of vial. If desired, you can centrifuge at 1000 rpm for 1 minute to concentrate volume in bottom of vial. This solution can be diluted into other buffered solutions containing carrier protein or medium containing serum and stored at 4 DEG C (up to 1 week) or -20 DEG C long term)

Storage: The lyophilized powder is stable at room temperature for a few weeks but it is best stored desiccated at -20 Deg C. Reconstituted RELM-ALPHA should be stored in working aliquots at -20 DEG C . AVOID FREQUENT FREEZE THAW CYCLES.

Reactivity: not determined

AA Sequence:



For In vitro research Use Only. Not for use in or onhumans or animals or for diagnostics.  It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


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