rev:  October 20, 2004

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Murine/Rat Cytokine/Growth Factor/Chemokines Sample Spec sheets (subject to change without notice):


DATA SHEET :  recombinant RAT Interleukin 4

Rat Interleukin 4 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. This Rat IL-4 is a 14kDa kDa protein containing 121 amino acid residues.

Catalog#: RDI-4004

Package Size: 10 micrograms $231.00/package   $219.00/package 2+

                       Mini-Pack: cat#RDI-4004p $94.00/2ug        Bulk quotes on request



Supplied: sterile filtered and Lyophilized protein, no carrier protein or other additives.

Source: E. Coli

Purity: >98% by SDS-Page analysis and HPLC analysis. Endotoxin level is less than 0.1ng per ug (1EU/ug) of rat IL-4.

Reconstitution: The lyophilized IL-4 is soluble in water and most aqueous (ph >7) buffers.   The lyophilized powder should be reconstituted in H20 to a concnetration of   0.1-1.0mg/ml.. Allow to set at least 30 minutes at 4 DEG C , tighten cap and   rotate to reconstitute any material on sides of vial. If desired, you can   centrifuge at 1000 rpm for 1 minute to concentrate volume in bottom of vial.   This solution can be diluted into water or other buffered solutions or stored at -20 DEG C for future use.



Note:If this material is not to be used for coating or labeling (or other applications requiring carrier free material), the addition of 0.1% BSA to dilution buffers or dilution in sterile culture media is recommended to enhance stability and minimize absorption to vial. Ideally, maintain stock >10ug/ml.

Storage: The lyophilized powder, though stable at room temperature, is best stored desiccated below 0 DEG C. Reconstituted rat IL-4 should be stored in working aliquots at -20 DEG C. Avoid Frequent Freeze-THAW Cycles.

Reactivity: This material is fully biologically active when compared to standards. The ED50 as determined by the dose dependent stimulation of the proliferation of con A-activated rat spleen cells was found to be <1.5ng/ml, yielding a specific activity of > 6.6 X 10 E06   units/mg

AA Sequence :

MHGCNDSPLR EIINTLNQVT EKGTPCTEMF VPDVLTATRN TTENELICRA

SRVLRKFYFP RDVPPCLKNK SGVLGELRKL CRGVSGLNSL RSCTVNESTL

TTLKDFLESL KSILRGKYLQ SCTSMS

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics.  It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


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