rev:   October 19, 2004

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Murine/Rat Cytokine/Growth Factor/Chemokines Sample Spec sheets (subject to change without notice):


DATA SHEET:  recombinant MURINE MIP-1 GAMMA

                    (murine Macrophage Inflammatory Protein 1 gamma)

-murine Macrophage inflammatory protein 1 gamma is a monokine with inflammatory, pyrogenic and chemokinetic CC properties. When murine MIP-1 gamma binds to a high affinity receptor it activates CC calcium release in neutrophils. It also inhibits colony formation CC of bone marrow myeloid immature progenitors. This rec mMIP-1g is an 11.6kDa protein containing 101 amino acid residues.

Catalog#: RDI-2512

Package Size:  20 micrograms $231.00/vial    $219.00/package 2+  BULK ON REQUEST

                          Mini-Pack:cat#RDI-2512P $94.00/5ug



Supplied: Lyophilized protein with no additives.

Source: E. Coli

Purity: >99% by SDS-Page analysis and HPLC analysis. Endotoxin level is less than 0.1ng per ug of MIP-1gamma

Reconstitution: The lyophilized MIP-g is soluble in water and most aqueous buffers. The lyophilized powder should be reconstituted in water to a concentration of 1mg/ml. Let sit at least 30 minutes, tighten cap, rotate vial to reconstitute any material on sides of vial. If desired, you can centrifuge the vial for 1-2 minutes at 1000 rpm to concentrate material in bottom of vial. This material can be diluted into water or other buffered solutions or stored at - 20 DEG C for future use. It is recommended that further dilutions of the stock be made into buffer containing carrier protein or media containing serum.

Storage: The lyophilized powder, though stable at room temperature, is best stored desiccated below 0 DEG C. Reconstituted MIP-1 gamma should be stored in working aliquots at -20 DEG C. Avoid Frequent Freeze-THAW Cycles.

Reactivity: The murine MIP-1g biological activity was determined by a chemotaxis assay. Significant chemotaxis was achieved at a concentration of 100ng/ml.

Precautions: For In vitro research Use Only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.


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