Murine/RAT Cytokine Data Sheets (Interleukin 22) available through RDI Division of Fitzgerald Industries Intl

rev: October 19, 2004

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Murine/Rat Cytokine/Growth Factor/Chemokines Sample Spec sheets (subject to change without notice):

DATA SHEET:recombinant Mouse INTERLEUKIN-22

-Murine IL-22 also known as T cell-derived inducible factor (ILTIF), is a cytokine that is structurally related to IL-10. Studies have shown that IL-22 induces acute-phase reactants in vitro and in vivo. This suggests that this cytokine contributes to the regulation of inflammatory responses. This recombinant Murine IL-22 is a 16.7 kDa protein consisting of 147 amino acid residues.

Catalog#: RDI-2222

Package Size: 10 micrograms $231.00 $219.00/package 2+

MINI-PACK:cat#RDI-2222P $94.00/2ug

-inquire for custom sizes/bulk packaging

Supplied: Lyophilized powder from 10mM NaCitrate pH4.0

Source: E. Coli

Purity: >97% by SDS-Page analysis and HPLC analysis. Endotoxin level less than 0.1ng/ug (1EU/ug)

Reconstitution: We recommend a quick spin followed by reconstitution in 10mM NaCitrate pH 4.0 or sterile DI water to a concentration of 0.1-1.0 mg/ml. Allow to set at least 30 minutes at 4 DEG C, tighten cap and rotate to reconstitute any material on sides of vial. If desired, you can centrifuge at 1000 rpm for 1 minute to concentrate volume in bottom of vial. This solution can be diluted into other buffered solutions containing carrier protein or medium containing serum and stored at 4 DEG C (up to 1 week) or -20 DEG C long term)

Storage: The lyophilized powder is stable at room temperature for a few weeks but it is best stored desiccated at -20 Deg C. Reconstituted IL-22 should be stored in working aliquots at -20 DEG C . AVOID FREQUENT FREEZE THAW CYCLES.

Reactivity: not determined

AA Sequence:

MLPVNTRCKL EVSNFQQPYI VNRTFMLAKE ASLADNNTDV RLIGEKLFRG

VSAKDQCYLM KQVLNFTLED VLLPQSDRFQ PYMQEVVPFL TKLSNQLSSC

HISGDDQNIQ KNVRRLKETV KKLGESGEIK AIGELDLLFM SLRNACV

For In vitro research Use Only. Not for use in or onhumans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. We are not responsible for any patent infringements that might result with the use of or derivation of this product.

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RDI Division of Fitzgerald Industries Intl

34 Junction Square Drive

Concord MA 01742-3049

USA

phone (978) 371-6446 or (800) 370-2222

fax (978) 371-2266