rev: 5/18/2008
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Human Cytokine/Growth Factor/Chemokines Sample Spec sheets (subject to change
without notice):
DATA SHEET:recombinant Insulin Like Growth Factor I
-The IGFs are mitogenic
polypeptide growth factors that stimulate the proliferation and survival of
various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a
variety of tissues produce the IGFs at distinctive
times. The IGFs belong to the Insulin gene family,
which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but
have a much higher growth-promoting activity than insulin. IGF-II expression is
influenced by placenta lactogen, while IGF-I
expression is regulated by growth hormone. Both IGF-I and IGF-II signal through
the tyrosine kinase type I
receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate
receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins,
which contain N-terminal and C-terminal propeptide
regions. This recombinant human IGF-I and IGF-II are globular proteins
containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide
bonds
Catalog#: RDI-111 DISCONTINUED. See
30-AI88.
Bulk, cat#RDI-111-216X $656.25/1mg
see also rec mouse ILGF1, cat#RDI-CYT229X $2125/mg $625.00/100ug
rec rat ILGF-1 cat#RDI-CYT289X $4000/mg $625.00/100ug
rec Chicken ILGF-1 cat#RDI-CYT290X $4000/mg $625.00/100ug
rec Tuna ILGF1 cat#RDI-CYT291X $4000/mg $625.00/100ug
rec Salmon/Trout ILGF1 cat#RDI-CYT293X $5000.00/mg $625.00/100ug
rec Bream ILGF1 cat#RDI-CYT294X $5000.00/mg $625.00/100ug
rec Barramundi ILGF1 cat#RDi-CYT292X $4000.00/mg $625.00/100ug
PLEASE CALL FOR BULK QUOTES!PLEASE CALL FOR BULK QUOTES! Also available monoclonal and polyclonal abs to IGF1, IGF2, IGFR, and IGFBP. see the antibody list.
phone (978) 371-6446 or (800) 370-2222
fax (978) 371-2266
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